Literature DB >> 21057892

Hypoglycaemia in a 63-year-old female with a large, recurrent, metastatic gastrointestinal stromal tumour (GIST).

Grace Tan1, Melissa Teo, Su Pin Choo.   

Abstract

INTRODUCTION: Non-islet cell tumour-induced hypoglycaemia (NICTH) is rare, with few cases reported in patients with gastrointestinal stromal tumour (GIST). CASE REPORT: A 63-year-old Chinese female with known metastatic GIST presents with persistent hypoglycaemia. Investigations revealed a likely diagnosis of NICTH, and she underwent debulking surgery. There was complete resolution of her hypoglycaemia post-operatively DISCUSSION: NICTH should be considered in patients with GIST and hypoglycaemia. Surgical debulking is recommended as part of the management of NICTH.

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Year:  2011        PMID： 21057892     DOI： 10.1007/s12029-010-9227-z

Source DB:  PubMed          Journal:  J Gastrointest Cancer


  9 in total

1.  Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: a report of two cases.

Authors:  Daniel Pink; Dagmar Schoeler; Tanja Lindner; Peter C Thuss-Patience; Albrecht Kretzschmar; Heike Knipp; Udo Vanhoefer; Peter Reichardt
Journal:  J Clin Oncol       Date:  2005-09-20       Impact factor: 44.544

2.  Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinib.

Authors:  Paul Hamberg; Floris A de Jong; Joke G Boonstra; Jaap van Doorn; Jaap Verweij; Stefan Sleijfer
Journal:  J Clin Oncol       Date:  2006-06-20       Impact factor: 44.544

3.  Non-hyperinsulinemic hypoglycemia in a patient with a gastrointestinal stromal tumor.

Authors:  R Singh; A Grey; M Miller; M G Gresnigt; C M Hoogerbrugge; J van Doorn
Journal:  Eur J Intern Med       Date:  2006-03       Impact factor: 4.487

4.  Surgical intervention following imatinib treatment in patients with advanced gastrointestinal stromal tumors (GISTs).

Authors:  Sun Jin Sym; Min-Hee Ryu; Jae-Lyun Lee; Heung Moon Chang; Tae-Won Kim; Hee Cheol Kim; Ki Hun Kim; Jeong Hwan Yook; Byung Sik Kim; Yoon-Koo Kang
Journal:  J Surg Oncol       Date:  2008-07-01       Impact factor: 3.454

5.  Hypoglycemia in the setting of advanced gastrointestinal stromal tumor.

Authors:  Jacfranz Guiteau; Michael Fanucchi; Andrew Folpe; Charles A Staley; David A Kooby
Journal:  Am Surg       Date:  2006-12       Impact factor: 0.688

6.  Surgical management of advanced gastrointestinal stromal tumors after treatment with targeted systemic therapy using kinase inhibitors.

Authors:  Chandrajit P Raut; Matthew Posner; Jayesh Desai; Jeffrey A Morgan; Suzanne George; David Zahrieh; Christopher D M Fletcher; George D Demetri; Monica M Bertagnolli
Journal:  J Clin Oncol       Date:  2006-05-20       Impact factor: 44.544

7.  Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors.

Authors:  W H Daughaday; M Kapadia
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

8.  The effectiveness of different treatment options for non-islet cell tumour hypoglycaemia.

Authors:  J D Teale; G Wark
Journal:  Clin Endocrinol (Oxf)       Date:  2004-04       Impact factor: 3.478

9.  Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report.

Authors:  Guillermo A Escobar; William A Robinson; Trevor L Nydam; Drew C Heiple; Glen J Weiss; Linda Buckley; Rene Gonzalez; Martin D McCarter
Journal:  BMC Cancer       Date:  2007-01-17       Impact factor: 4.430
  9 in total
  1 in total

Review 1.  Management of non-islet-cell tumor hypoglycemia: a clinical review.

Authors:  Timothy W Bodnar; Maria J Acevedo; Massimo Pietropaolo
Journal:  J Clin Endocrinol Metab       Date:  2013-12-11       Impact factor: 5.958
  1 in total

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