Literature DB >> 21057660

Cyanobacterial Blooms and the Occurrence of the neurotoxin beta-N-methylamino-L-alanine (BMAA) in South Florida Aquatic Food Webs.

Larry E Brand1, John Pablo, Angela Compton, Neil Hammerschlag, Deborah C Mash.   

Abstract

Recent studies demonstrate that most cyanobacteria produce the neurotoxin beta-N-methylamino-L-alanine (BMAA) and that it can biomagnify in at least one terrestrial food chain. BMAA has been implicated as a significant environmental risk in the development of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis (ALS). We examined several blooms of cyanobacteria in South Florida, and the BMAA content of resident animals, including species used as human food. A wide range of BMAA concentrations were found, ranging from below assay detection limits to approximately 7000 μg/g, a concentration associated with a potential long-term human health hazard.

Entities:  

Year:  2010        PMID: 21057660      PMCID: PMC2968748          DOI: 10.1016/j.hal.2010.05.002

Source DB:  PubMed          Journal:  Harmful Algae        ISSN: 1568-9883            Impact factor:   4.273


  42 in total

1.  Long-term history of chesapeake bay anoxia.

Authors:  S R Cooper; G S Brush
Journal:  Science       Date:  1991-11-15       Impact factor: 47.728

2.  Cyanobacterial toxins: a qualitative meta-analysis of concentrations, dosage and effects in freshwater, estuarine and marine biota.

Authors:  Bas W Ibelings; Karl E Havens
Journal:  Adv Exp Med Biol       Date:  2008       Impact factor: 2.622

Review 3.  Hydrolysis and amino acid composition of proteins.

Authors:  M Fountoulakis; H W Lahm
Journal:  J Chromatogr A       Date:  1998-11-27       Impact factor: 4.759

Review 4.  Alzheimer's disease: current knowledge, management and research.

Authors:  S Gauthier; M Panisset; J Nalbantoglu; J Poirier
Journal:  CMAJ       Date:  1997-10-15       Impact factor: 8.262

5.  Organ distribution and bioaccumulation of microcystins in freshwater fish at different trophic levels from the eutrophic Lake Chaohu, China.

Authors:  Liqiang Xie; Ping Xie; Longgen Guo; Li Li; Yuichi Miyabara; Ho-Dong Park
Journal:  Environ Toxicol       Date:  2005-06       Impact factor: 4.119

6.  Occurrence of beta-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam.

Authors:  S J Murch; P A Cox; S A Banack; J C Steele; O W Sacks
Journal:  Acta Neurol Scand       Date:  2004-10       Impact factor: 3.209

7.  Beta-N-methylamino-L-alanine (BMAA) in novel South African cyanobacterial isolates.

Authors:  M Esterhuizen; T G Downing
Journal:  Ecotoxicol Environ Saf       Date:  2008-06-05       Impact factor: 6.291

8.  Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam.

Authors:  Paul Alan Cox; Sandra Anne Banack; Susan J Murch
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-11       Impact factor: 11.205

9.  Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins.

Authors:  W W Carmichael; S M Azevedo; J S An; R J Molica; E M Jochimsen; S Lau; K L Rinehart; G R Shaw; G K Eaglesham
Journal:  Environ Health Perspect       Date:  2001-07       Impact factor: 9.031

Review 10.  The role of glutamate transporters in glutamate homeostasis in the brain.

Authors:  M Takahashi; B Billups; D Rossi; M Sarantis; M Hamann; D Attwell
Journal:  J Exp Biol       Date:  1997-01       Impact factor: 3.312

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  66 in total

Review 1.  The Potential Role of BMAA in Neurodegeneration.

Authors:  Tracie Caller; Patricia Henegan; Elijah Stommel
Journal:  Neurotox Res       Date:  2017-06-13       Impact factor: 3.911

2.  Assessment of the non-protein amino acid BMAA in Mediterranean mussel Mytilus galloprovincialis after feeding with estuarine cyanobacteria.

Authors:  Mafalda S Baptista; Rita G W Vasconcelos; Paula C Ferreira; C Marisa R Almeida; Vitor M Vasconcelos
Journal:  Environ Sci Pollut Res Int       Date:  2015-04-24       Impact factor: 4.223

3.  Creating a Simian Model of Guam ALS/PDC Which Reflects Chamorro Lifetime BMAA Exposures.

Authors:  Sandra Anne Banack; Paul Alan Cox
Journal:  Neurotox Res       Date:  2017-05-06       Impact factor: 3.911

Review 4.  A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans.

Authors:  N Chernoff; D J Hill; D L Diggs; B D Faison; B M Francis; J R Lang; M M Larue; T-T Le; K A Loftin; J N Lugo; J E Schmid; W M Winnik
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2017-06-09       Impact factor: 6.393

5.  N-β-Methylamino-L-Alanine and Its Naturally Occurring Isomers in Cyanobacterial Blooms in Lake Winnipeg.

Authors:  Stephanie L Bishop; Jeff K Kerkovius; Frederic Menard; Susan J Murch
Journal:  Neurotox Res       Date:  2017-09-30       Impact factor: 3.911

6.  Exposure to BMAA mirrors molecular processes linked to neurodegenerative disease.

Authors:  Joshua Beri; Tara Nash; Rubia M Martin; Michael S Bereman
Journal:  Proteomics       Date:  2017-08-24       Impact factor: 3.984

7.  The Evaluation of BMAA Inhalation as a Potential Exposure Route Using a rat Model.

Authors:  Laura Louise Scott; Simoné Downing; Timothy Grant Downing
Journal:  Neurotox Res       Date:  2017-05-03       Impact factor: 3.911

8.  High resolution metabolite imaging in the hippocampus following neonatal exposure to the environmental toxin BMAA using ToF-SIMS.

Authors:  Jörg Hanrieder; Lorenz Gerber; Åsa Persson Sandelius; Eva B Brittebo; Andrew G Ewing; Oskar Karlsson
Journal:  ACS Chem Neurosci       Date:  2014-05-09       Impact factor: 4.418

9.  Detection of the Cyanotoxins L-BMAA Uptake and Accumulation in Primary Neurons and Astrocytes.

Authors:  Vanessa X Tan; Claire Mazzocco; Bianca Varney; Dominique Bodet; Tristan A Guillemin; Alban Bessede; Gilles J Guillemin
Journal:  Neurotox Res       Date:  2017-08-30       Impact factor: 3.911

Review 10.  Current pathways for epidemiological research in amyotrophic lateral sclerosis.

Authors:  Pam Factor-Litvak; Ammar Al-Chalabi; Alberto Ascherio; Walter Bradley; Adriano Chío; Ralph Garruto; Orla Hardiman; Freya Kamel; Edward Kasarskis; Ann McKee; Imaharu Nakano; Lorene M Nelson; Andrew Eisen
Journal:  Amyotroph Lateral Scler Frontotemporal Degener       Date:  2013-05       Impact factor: 4.092

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