OBJECTIVE: We hypothesized that preeclampsia partly shares pathophysiology with stillbirth, placental abruption, spontaneous preterm birth, and giving birth to a small-for-gestational-age infant, and that women who develop preeclampsia in the first pregnancy may have increased risks of the other outcomes in the second pregnancy, even in the absence of preeclampsia. STUDY DESIGN: In a nationwide Swedish cohort (n = 354,676) we estimated risks of adverse outcomes in the second pregnancy related to preterm (< 37 weeks) and term (≥ 37 weeks) preeclampsia in the first pregnancy, using women without preeclampsia in the first pregnancy as reference. RESULTS: Women with prior preterm preeclampsia had, in second pregnancy, more than doubled risks of stillbirth, placental abruption, and preterm births, and an even greater risk of giving birth to a small-for-gestational-age infant. CONCLUSION: Women with previous preterm preeclampsia have increased risks of adverse pregnancy outcomes in a second pregnancy despite the absence of preeclampsia.
OBJECTIVE: We hypothesized that preeclampsia partly shares pathophysiology with stillbirth, placental abruption, spontaneous preterm birth, and giving birth to a small-for-gestational-age infant, and that women who develop preeclampsia in the first pregnancy may have increased risks of the other outcomes in the second pregnancy, even in the absence of preeclampsia. STUDY DESIGN: In a nationwide Swedish cohort (n = 354,676) we estimated risks of adverse outcomes in the second pregnancy related to preterm (< 37 weeks) and term (≥ 37 weeks) preeclampsia in the first pregnancy, using women without preeclampsia in the first pregnancy as reference. RESULTS:Women with prior preterm preeclampsia had, in second pregnancy, more than doubled risks of stillbirth, placental abruption, and preterm births, and an even greater risk of giving birth to a small-for-gestational-age infant. CONCLUSION:Women with previous preterm preeclampsia have increased risks of adverse pregnancy outcomes in a second pregnancy despite the absence of preeclampsia.
Authors: Samantha E Parker; Martha M Werler; Mika Gissler; Minna Tikkanen; Cande V Ananth Journal: Paediatr Perinat Epidemiol Date: 2015-03-11 Impact factor: 3.980
Authors: Hamisu M Salihu; Abraham Salinas; Euna M August; Mulubrhan F Mogos; Hanna Weldeselasse; Valerie E Whiteman Journal: Ann Epidemiol Date: 2012-08-02 Impact factor: 3.797
Authors: Edailna Maria de Melo Dantas; Flávio Venicio Marinho Pereira; José Wilton Queiroz; Diogo Luis de Melo Dantas; Gloria Regina Gois Monteiro; Priya Duggal; Maria de Fatima Azevedo; Selma Maria Bezerra Jeronimo; Ana Cristina Pinheiro Fernandes Araújo Journal: BMC Pregnancy Childbirth Date: 2013-08-08 Impact factor: 3.007
Authors: Pia M Villa; Pekka Marttinen; Jussi Gillberg; A Inkeri Lokki; Kerttu Majander; Maija-Riitta Ordén; Pekka Taipale; Anukatriina Pesonen; Katri Räikkönen; Esa Hämäläinen; Eero Kajantie; Hannele Laivuori Journal: PLoS One Date: 2017-03-28 Impact factor: 3.240
Authors: Martin Andreas; Lorenz Kuessel; Stefan P Kastl; Stefan Wirth; Kathrin Gruber; Franziska Rhomberg; Fatemeh A Gomari-Grisar; Maximilian Franz; Harald Zeisler; Michael Gottsauner-Wolf Journal: BMC Pregnancy Childbirth Date: 2016-06-01 Impact factor: 3.007