Literature DB >> 21054747

Iron deficiency anaemia and delayed diagnosis of colorectal cancer: a retrospective cohort study.

S Damery1, R Ryan, S Wilson, T Ismail, R Hobbs.   

Abstract

AIM: The extent to which different referral pathways following a primary care diagnosis of iron deficiency anaemia (IDA) are associated with delay in diagnosis of colorectal cancer (CRC) was determined.
METHOD: Eligible patients aged 40 or more years, with IDA diagnosed in primary care, and a subsequent diagnosis of CRC, were studied retrospectively. Referral pathways were identified using the specialty of first recorded GP referral following IDA diagnosis. Differences in time to diagnosis of CRC were assessed by referral specialty. Differences in the proportion of cases referred before and after the re-issue of the NICE urgent referral guidelines for suspected lower gastrointestinal (GI) cancer were also assessed.
RESULTS: Of 628,882 eligible patients, 3.1% (n = 19,349) were diagnosed with IDA during the study period; 3.0% (n = 578) were subsequently diagnosed with CRC. Two hundred and fifty-nine (44.8%) patients had no recorded referral or a referral unrelated to anaemia or the GI tract. Only 35% (n = 201) of patients were referred to a relevant specialty. Median time to CRC diagnosis ranged from 2.5 months (referral to a relevant surgical specialty) to 31.9 months (haematology). Time to diagnosis was longer in patients referred to a medical compared with a relevant surgical specialty (P = 0.024). There was no significant difference in time to CRC diagnosis before and after the NICE guidelines were re-issued in 2005.
CONCLUSION: Significant differences exist between referral specialties in time to CRC diagnosis following a primary care diagnosis of IDA. Despite NICE referral recommendations, a significant proportion of patients are still not managed within recommended care pathways to CRC diagnosis.
© 2011 The Authors. Colorectal Disease © 2011 The Association of Coloproctology of Great Britain and Ireland.

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Mesh:

Year:  2011        PMID: 21054747     DOI: 10.1111/j.1463-1318.2010.02488.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  6 in total

1.  The development of a nurse-led iron deficiency anaemia service in a district general hospital.

Authors:  Susan L Surgenor; Silvia Kirkham; Sally D Parry; Elizabeth J Williams; Jonathon A Snook
Journal:  Frontline Gastroenterol       Date:  2013-12-17

2.  The yield of colorectal cancer among fast track patients with normocytic and microcytic anaemia.

Authors:  I G Panagiotopoulou; D Fitzrol; R A Parker; J Kuzhively; N Luscombe; A D Wells; M Menon; F M Bajwa; M A Watson
Journal:  Ann R Coll Surg Engl       Date:  2014-05       Impact factor: 1.891

3.  Electronic ambulance chasing: patient records, guidelines, and the law.

Authors:  Tom Marshall
Journal:  Br J Gen Pract       Date:  2015-03       Impact factor: 5.386

4.  Validity and completeness of colorectal cancer diagnoses in a primary care database in the United Kingdom.

Authors:  Lucía Cea Soriano; Montse Soriano-Gabarró; Luis A García Rodríguez
Journal:  Pharmacoepidemiol Drug Saf       Date:  2015-10-05       Impact factor: 2.890

5.  Development and validation of a predictive model for detection of colorectal cancer in primary care by analysis of complete blood counts: a binational retrospective study.

Authors:  Yaron Kinar; Nir Kalkstein; Pinchas Akiva; Bernard Levin; Elizabeth E Half; Inbal Goldshtein; Gabriel Chodick; Varda Shalev
Journal:  J Am Med Inform Assoc       Date:  2016-02-15       Impact factor: 4.497

6.  Missed Opportunities for the Diagnosis of Colorectal Cancer.

Authors:  Laura A Siminoff; Heather L Rogers; Sonja Harris-Haywood
Journal:  Biomed Res Int       Date:  2015-10-04       Impact factor: 3.411

  6 in total

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