Literature DB >> 21054392

Therapeutic potential of argan oil: a review.

Hanae El Monfalouti1, Dom Guillaume, Clément Denhez, Zoubida Charrouf.   

Abstract

OBJECTIVES: The therapeutic benefits of argan oil consumption have been claimed by natives of Morocco and explorers for more than eight centuries. However, argan oil has remained unresearched for a long time. Traditionally, argan oil has been well known for its cardioprotective properties and it is also used in the treatment of skin infections. Argan oil is principally composed of mono-unsaturated (up to 80%) and saturated (up to 20%) fatty acids. As minor components, it contains polyphenols, tocopherols, sterols, squalene, and triterpene alcohols. Together with the mono-unsaturated fatty acids, these minor components are likely to be responsible for its beneficial effects. This review aims to present an overview of the known pharmacological properties of argan oil. KEY
FINDINGS: Antiproliferative, antidiabetic, and cardiovascular-protective effects of argan oil have been particularly actively evaluated over the last 5 years in order to build on phytochemical studies that indicate the presence of large amounts of possibly pharmacologically active compounds.
SUMMARY: This review shows that a lack of clinical data constitutes a serious weakness in our knowledge about argan oil, therefore it is difficult to correlate the reported pharmacological activities to any potential clinical relevance.
© 2010 The Authors. JPP © 2010 Royal Pharmaceutical Society of Great Britain.

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Year:  2010        PMID: 21054392     DOI: 10.1111/j.2042-7158.2010.01190.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  16 in total

1.  Influence of argan kernel roasting-time on virgin argan oil composition and oxidative stability.

Authors:  Hicham Harhar; Saïd Gharby; Bader Kartah; Hanae El Monfalouti; Dom Guillaume; Zoubida Charrouf
Journal:  Plant Foods Hum Nutr       Date:  2011-06       Impact factor: 3.921

2.  Effects of a Short-Term Lipopolysaccharides Challenge on Mouse Brain and Liver Peroxisomal Antioxidant and β-oxidative Functions: Protective Action of Argan Oil.

Authors:  Soukaina Essadek; Habiba Bouchab; Riad El Kebbaj; Catherine Gondcaille; Soufiane El Kamouni; Stéphane Savary; Joseph Vamecq; Abdelkhalid Essamadi; Mustapha Cherkaoui-Malki; Boubker Nasser; Pierre Andreoletti
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-12

3.  Argan Oil Exerts an Antiatherogenic Effect by Improving Lipids and Susceptibility of LDL to Oxidation in Type 2 Diabetes Patients.

Authors:  M M Ould Mohamedou; K Zouirech; M El Messal; M S El Kebbaj; A Chraibi; A Adlouni
Journal:  Int J Endocrinol       Date:  2011-11-01       Impact factor: 3.257

4.  The Antioxidant Content and Protective Effect of Argan Oil and Syzygium aromaticum Essential Oil in Hydrogen Peroxide-Induced Biochemical and Histological Changes.

Authors:  Meryem Bakour; Najoua Soulo; Nawal Hammas; Hinde El Fatemi; Abderrazak Aboulghazi; Amal Taroq; Abdelfattah Abdellaoui; Noori Al-Waili; Badiaa Lyoussi
Journal:  Int J Mol Sci       Date:  2018-02-18       Impact factor: 5.923

5.  In Vitro & In Vivo Anti-Hyperglycemic Potential of Saponins Cake and Argan Oil from Argania spinosa.

Authors:  Rabie Kamal; Mourad Kharbach; Yvan Vander Heyden; Huiwen Yu; Abdelaziz Bouklouze; Yahia Cherrah; Katim Alaoui
Journal:  Foods       Date:  2021-05-13

6.  Argan oil prevents prothrombotic complications by lowering lipid levels and platelet aggregation, enhancing oxidative status in dyslipidemic patients from the area of Rabat (Morocco).

Authors:  Adil Haimeur; Hafida Messaouri; Lionel Ulmann; Virginie Mimouni; Azelarab Masrar; Abdelmjid Chraibi; Gérard Tremblin; Nadia Meskini
Journal:  Lipids Health Dis       Date:  2013-07-20       Impact factor: 3.876

7.  Activation of MITF by Argan Oil Leads to the Inhibition of the Tyrosinase and Dopachrome Tautomerase Expressions in B16 Murine Melanoma Cells.

Authors:  Myra O Villareal; Sayuri Kume; Thouria Bourhim; Fatima Zahra Bakhtaoui; Kenichi Kashiwagi; Junkyu Han; Chemseddoha Gadhi; Hiroko Isoda
Journal:  Evid Based Complement Alternat Med       Date:  2013-07-08       Impact factor: 2.629

8.  Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.

Authors:  Asmaa Badreddine; Amira Zarrouk; El Mostafa Karym; Meryam Debbabi; Thomas Nury; Wiem Meddeb; Randa Sghaier; Maryem Bezine; Anne Vejux; Lucy Martine; Stéphane Grégoire; Lionel Bretillon; Emmanuelle Prost-Camus; Philippe Durand; Michel Prost; Thibault Moreau; Mustapha Cherkaoui-Malki; Boubker Nasser; Gérard Lizard
Journal:  Int J Mol Sci       Date:  2017-10-23       Impact factor: 5.923

9.  Preliminary study on the development of an antistretch marks water-in-oil cream: ultrasound assessment, texture analysis, and sensory analysis.

Authors:  Cătălina Bogdan; Mirela L Moldovan; Ioana Manuela Man; Maria Crișan
Journal:  Clin Cosmet Investig Dermatol       Date:  2016-09-06

Review 10.  The Enigma of Bioactivity and Toxicity of Botanical Oils for Skin Care.

Authors:  Erin M Moore; Charles Wagner; Slavko Komarnytsky
Journal:  Front Pharmacol       Date:  2020-05-29       Impact factor: 5.810

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