| Literature DB >> 21054170 |
Barbara C Silva1, John P Bilezikian.
Abstract
Although safe and effective agents are currently available to treat osteoporosis, fragility fractures remain a significant problem worldwide. Recent improvements in the understanding of the cellular, biochemical, and molecular pathways of bone biology have led to the development of newer agents to treat osteoporosis, which may lead to further improvements in outcomes. In this review, we summarize the most recent advances in the field, including new modes of administration of existing drug classes, various approaches to combination therapy, and drugs with novel mechanisms of action to treat osteoporosis.Entities:
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Year: 2011 PMID： 21054170 DOI： 10.1146/annurev-med-061709-145401
Source DB: PubMed Journal: Annu Rev Med ISSN： 0066-4219 Impact factor: 13.739