Literature DB >> 21053528

Modern radiotherapy and cervical cancer.

Melanie E B Powell1.   

Abstract

For most cervical cancers, radiotherapy is the mainstay of treatment. The introduction of concurrent chemotherapy to radiation at the end of the 20th century led to a significant improvement in disease survival. Now, techniques such as intensity-modulated radiotherapy, which allow a high degree of conformity to the tumor, offer the opportunity to further improve outcome by reducing treatment-related toxicity and also to potentially improve local control by an increase in tumor dose. This review will outline the history and current state of play of cervical radiotherapy.

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Year:  2010        PMID: 21053528     DOI: 10.1111/igc.0b013e3181f7b241

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  14 in total

1.  Long non-coding RNA MALAT1 modulates radiosensitivity of HR-HPV+ cervical cancer via sponging miR-145.

Authors:  Hongzhi Lu; Yu He; Lin Lin; Zhengqin Qi; Li Ma; Li Li; Ying Su
Journal:  Tumour Biol       Date:  2015-08-27

2.  The poly (ADP-ribose) polymerase inhibitor rucaparib suppresses proliferation and serves as an effective radiosensitizer in cervical cancer.

Authors:  Mei Tang; Qiuli Liu; Leyuan Zhou; Ling Chen; Xueqing Yang; Jinjin Yu; Yuan Wang; Haifeng Qiu
Journal:  Invest New Drugs       Date:  2018-06-06       Impact factor: 3.850

3.  Changes in prevalence and clinical characteristics of cervical cancer in the People's Republic of China: a study of 10,012 cases from a nationwide working group.

Authors:  Shuang Li; Ting Hu; Weiguo Lv; Hang Zhou; Xiong Li; Ru Yang; Yao Jia; Kecheng Huang; Zhilan Chen; Shaoshuai Wang; Fangxu Tang; Qinghua Zhang; Jian Shen; Jin Zhou; Ling Xi; Dongrui Deng; Hui Wang; Shixuan Wang; Xing Xie; Ding Ma
Journal:  Oncologist       Date:  2013-09-16

4.  MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt-mTOR signaling pathway.

Authors:  Lili Song; Shikai Liu; Liang Zhang; Hairong Yao; Fangyuan Gao; Dongkui Xu; Qian Li
Journal:  Tumour Biol       Date:  2016-05-25

Review 5.  microRNA-21: a key modulator in oncogenic viral infections.

Authors:  Guitian He; Juntao Ding; Yong'e Zhang; Mengting Cai; Jing Yang; William C Cho; Yadong Zheng
Journal:  RNA Biol       Date:  2021-03-22       Impact factor: 4.652

6.  MicroRNA-218 enhances the radiosensitivity of human cervical cancer via promoting radiation induced apoptosis.

Authors:  Wang Yuan; Han Xiaoyun; Qiu Haifeng; Li Jing; Hu Weixu; Dong Ruofan; Yu Jinjin; Shen Zongji
Journal:  Int J Med Sci       Date:  2014-05-06       Impact factor: 3.738

7.  miR-424 acts as a tumor radiosensitizer by targeting aprataxin in cervical cancer.

Authors:  Xia Wang; Qing Li; Hua Jin; Hua Zou; Wei Xia; Nan Dai; Xiao-Yan Dai; Dong Wang; Cheng-Xiong Xu; Yi Qing
Journal:  Oncotarget       Date:  2016-11-22

8.  miR-375 Modulates Radiosensitivity of HR-HPV-Positive Cervical Cancer Cells by Targeting UBE3A through the p53 Pathway.

Authors:  Lili Song; Shikai Liu; Saitian Zeng; Liang Zhang; Xia Li
Journal:  Med Sci Monit       Date:  2015-07-30

9.  Utility of serum squamous cell carcinoma antigen levels at the time of recurrent cervical cancer diagnosis in determining the optimal treatment choice.

Authors:  Kotaro Shimura; Seiji Mabuchi; Takeshi Yokoi; Tomoyuki Sasano; Kenjirou Sawada; Toshimitsu Hamasaki; Tadashi Kimura
Journal:  J Gynecol Oncol       Date:  2013-10-02       Impact factor: 4.401

10.  GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level.

Authors:  Qing Li; Xi Wei; Zhi-Wei Zhou; Shu-Nan Wang; Hua Jin; Kui-Jun Chen; Jia Luo; Kenneth D Westover; Jian-Min Wang; Dong Wang; Cheng-Xiong Xu; Jin-Lu Shan
Journal:  Cell Death Dis       Date:  2018-05-01       Impact factor: 8.469

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