Literature DB >> 21052996

Laparoscopic antireflux surgery in patients with throat symptoms: a word of caution.

Dharmendran Ratnasingam1, Tanya Irvine, Sarah K Thompson, David I Watson.   

Abstract

BACKGROUND: A subset of patients undergoing laparoscopic fundoplication presents with atypical throat symptoms, and the benefit of surgery in these patients is debated. These patients can present with throat symptoms alone or in combination with typical reflux symptoms. We evaluated the clinical outcome in these patients and compared their outcomes with a larger group of patients who did not have throat symptoms before fundoplication.
METHODS: Outcome data for 893 consecutive patients who underwent a laparoscopic fundoplication from January 2002 to June 2008 were collected prospectively and managed on a database. Ninety-three patients with atypical throat symptoms were identified, and divided into subgroups with (n=66) and without (n=27) typical reflux symptoms (heartburn and/or regurgitation), and outcomes were compared with patients (n=800) who didn't have throat symptoms. Symptoms were assessed with analog symptom scores for heartburn and dysphagia, as well as satisfaction with the surgical outcome. Case records for patients with throat symptoms were also reviewed to obtain more detail about specific throat symptoms and their resolution.
RESULTS: Cough was the commonest atypical symptom, followed by sore throat. Heartburn scores improved following surgery in all patient groups. Dysphagia was more common 3 months after surgery in patients without throat symptoms, although there were no differences for dysphagia at later follow-up. Following surgery satisfaction scores were highest in patients with atypical throat symptoms who also had typical reflux symptoms, and the scores were lowest in patients who only had atypical throat symptoms. Nearly twice as many patients who had throat and reflux symptoms reported improvement or resolution of symptoms, compared to patients who only had throat symptoms.
CONCLUSIONS: Fundoplication achieves a good outcome in patients with atypical throat symptoms who also report typical symptoms of reflux. However, surgeons should be cautious about operating on the subgroup of patients with objective evidence of gastroesophageal reflux who describe throat symptoms but do not report heartburn or regurgitation. In this subgroup, expectations of a good outcome should be minimized.

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Year:  2011        PMID: 21052996     DOI: 10.1007/s00268-010-0838-0

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  14 in total

1.  Ten-year clinical outcome of a prospective randomized clinical trial of laparoscopic Nissen versus anterior 180( degrees ) partial fundoplication.

Authors:  W Cai; D I Watson; C J Lally; P G Devitt; P A Game; G G Jamieson
Journal:  Br J Surg       Date:  2008-12       Impact factor: 6.939

Review 2.  Evaluation and management of laryngopharyngeal reflux.

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3.  Results of laparoscopic fundoplication where atypical symptoms coexist with oesophageal reflux.

Authors:  R Y Chen; R J Thomas
Journal:  Aust N Z J Surg       Date:  2000-12

4.  Response of atypical symptoms of gastro-oesophageal reflux to antireflux surgery.

Authors:  T M Farrell; W S Richardson; T L Trus; C D Smith; J G Hunter
Journal:  Br J Surg       Date:  2001-12       Impact factor: 6.939

5.  Determinants of long-term outcome of patients with reflux-related ear, nose, and throat symptoms.

Authors:  Johan Poelmans; Louw Feenstra; Jan Tack
Journal:  Dig Dis Sci       Date:  2006-02       Impact factor: 3.199

6.  Long-term comparative outcome between laparoscopic total Nissen and Toupet fundoplication: Symptomatic relief, patient satisfaction and quality of life.

Authors:  B Sgromo; L A Irvine; A Cuschieri; S M Shimi
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7.  Outcome of surgical fundoplication for extra-oesophageal symptoms of reflux.

Authors:  Mohd Iqbal; A J Batch; Krishna Moorthy; B T Cooper; R T Spychal
Journal:  Surg Endosc       Date:  2008-03-26       Impact factor: 4.584

8.  Laparoscopic Nissen fundoplication: clinical outcomes at 10 years.

Authors:  Jamie J Kelly; David I Watson; Kin Fah Chin; Peter G Devitt; Philip A Game; Glyn G Jamieson
Journal:  J Am Coll Surg       Date:  2007-08-23       Impact factor: 6.113

9.  Recurrent symptoms after fundoplication with a negative pH study--recurrent reflux or functional heartburn?

Authors:  Sarah K Thompson; Wang Cai; Glyn G Jamieson; Alison Y Zhang; Jennifer C Myers; Zoe E Parr; David I Watson; Jenny Persson; Gerald Holtmann; Peter G Devitt
Journal:  J Gastrointest Surg       Date:  2008-08-20       Impact factor: 3.452

10.  Fundoplication for laryngopharyngeal reflux disease.

Authors:  Carl J Westcott; M Benjamin Hopkins; Kevin Bach; Gregory N Postma; Peter C Belafsky; James A Koufman
Journal:  J Am Coll Surg       Date:  2004-07       Impact factor: 6.113

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Journal:  Gastroenterol Hepatol (N Y)       Date:  2014-09

2.  New developments in extraesophageal reflux disease.

Authors:  Elif Saritas Yuksel; Michael F Vaezi
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3.  Causes of dissatisfaction after laparoscopic fundoplication: the impact of new symptoms, recurrent symptoms, and the patient experience.

Authors:  Leigh A Humphries; Jonathan M Hernandez; Whalen Clark; Kenneth Luberice; Sharona B Ross; Alexander S Rosemurgy
Journal:  Surg Endosc       Date:  2013-03-19       Impact factor: 4.584

Review 4.  Laryngopharyngeal reflux: diagnosis, treatment, and latest research.

Authors:  Andrea Maria Campagnolo; Jaqueline Priston; Rebecca Heidrich Thoen; Tatiana Medeiros; Aída Regina Assunção
Journal:  Int Arch Otorhinolaryngol       Date:  2013-11-05

Review 5.  Efficacy of acid suppression therapy in gastroesophageal reflux disease-related chronic laryngitis.

Authors:  Yue Yang; Haitao Wu; Jian Zhou
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

  5 in total

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