Literature DB >> 21052696

Bradycardia without associated hypertension: a common sign of ventriculo-peritoneal shunt malfunction.

John H Livingston1, Helen G McCullagh, Gagan Kooner, Anne-Marie Childs, Paul Chumas, Atul Tyagi, John C Taylor.   

Abstract

INTRODUCTION: Delayed diagnosis of ventriculo-peritoneal (VP) shunt malfunction results in avoidable morbidity and mortality. One reason is that most of the signs of shunt malfunction have low specificity.
OBJECTIVE: The objective of this study was to evaluate the presence of bradycardia as a sign of VP shunt malfunction in children with treated hydrocephalus.
METHODS: Children presenting with clinical features suggestive of possible VP shunt malfunction were retrospectively identified. Children with confirmed shunt malfunction formed the study group. Those who did not have shunt malfunction formed the control group, and the symptoms and signs were compared between the two groups. In particular, the presence of bradycardia (a heart rate less than the second centile of age-related norms) was sought. The positive predictive value (PPV) of bradycardia was compared with other common features of shunt malfunction.
RESULTS: Data were obtained for 52 patients: 34 in the study group (data from 40 admissions) and 18 controls. Bradycardia was present in 18 of 40 (45%) of the study group and 2 of 18(11%) controls (p = 0.011). Only two of the patients with bradycardia had associated hypertension. The PPV for bradycardia was 90% compared with 92% for reduced conscious level and 65% for both headache and vomiting (the four commonest presenting features).
CONCLUSIONS: Bradycardia without hypertension is common in children with VP shunt malfunction. The significance of bradycardia is often not recognised; the value of this sign should be emphasised.

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Year:  2010        PMID: 21052696     DOI: 10.1007/s00381-010-1315-7

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  11 in total

1.  The incidence of bradycardia during endoscopic third ventriculostomy.

Authors:  A A El-Dawlatly; W R Murshid; A Elshimy; M A Magboul; A Samarkandi; M S Takrouri
Journal:  Anesth Analg       Date:  2000-11       Impact factor: 5.108

2.  Intraoperative bradycardia and postoperative hyperkalemia in patients undergoing endoscopic third ventriculostomy.

Authors:  B Anandh; K R Madhusudan Reddy; A Mohanty; G S Umamaheswara Rao; B A Chandramouli
Journal:  Minim Invasive Neurosurg       Date:  2002-09

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Authors:  B J Iskandar; S Tubbs; T B Mapstone; P A Grabb; A A Bartolucci; W J Oakes
Journal:  Pediatr Neurosurg       Date:  1998-04       Impact factor: 1.162

5.  Predicting shunt failure on the basis of clinical symptoms and signs in children.

Authors:  H J Garton; J R Kestle; J M Drake
Journal:  J Neurosurg       Date:  2001-02       Impact factor: 5.115

6.  Development of a modified paediatric coma scale in intensive care clinical practice.

Authors:  A Tatman; A Warren; A Williams; J E Powell; W Whitehouse
Journal:  Arch Dis Child       Date:  1997-12       Impact factor: 3.791

7.  Long-term reliability of endoscopic third ventriculostomy.

Authors:  David Kadrian; James van Gelder; Danielle Florida; Robert Jones; Marianne Vonau; Charles Teo; Warwick Stening; Bernard Kwok
Journal:  Neurosurgery       Date:  2005-06       Impact factor: 4.654

8.  Report of the Second Task Force on Blood Pressure Control in Children--1987. Task Force on Blood Pressure Control in Children. National Heart, Lung, and Blood Institute, Bethesda, Maryland.

Authors: 
Journal:  Pediatrics       Date:  1987-01       Impact factor: 7.124

9.  Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus.

Authors:  J M Drake; J R Kestle; R Milner; G Cinalli; F Boop; J Piatt; S Haines; S J Schiff; D D Cochrane; P Steinbok; N MacNeil
Journal:  Neurosurgery       Date:  1998-08       Impact factor: 4.654

10.  Ventriculoperitoneal shunt block: what are the best predictive clinical indicators?

Authors:  N P Barnes; S J Jones; R D Hayward; W J Harkness; D Thompson
Journal:  Arch Dis Child       Date:  2002-09       Impact factor: 3.791

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  1 in total

1.  Bradycardia without associated hypertension.

Authors:  Viroj Wiwanitkit
Journal:  Childs Nerv Syst       Date:  2011-05-26       Impact factor: 1.475

  1 in total

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