| Literature DB >> 21052074 |
Eng H Lo1.
Abstract
Divergent disease triggers in neurodegeneration may induce convergent endogenous pathways in neuronal, glial and vascular elements as the central nervous system (CNS) attempts to compensate, remodel and recover. Dissecting these multicellular mechanisms and the integrative responses in cerebral blood flow and metabolism may allow us to understand the balance between injury and repair, validate new targets and define therapeutic time windows for neurodegeneration.Entities:
Mesh:
Year: 2010 PMID: 21052074 PMCID: PMC3985732 DOI: 10.1038/nm.2226
Source DB: PubMed Journal: Nat Med ISSN: 1078-8956 Impact factor: 53.440