Literature DB >> 21051228

The identification of novel orally active mGluR5 antagonist GSK2210875.

Maria Pilla1, Michela Andreoli, Michela Tessari, Sonia Delle-Fratte, Adelheid Roth, Sharon Butler, Fiona Brown, Parita Shah, Ezio Bettini, Palmina Cavallini, Roberto Benedetti, Doug Minick, Paul Smith, Ben Tehan, Pier D'Alessandro, Olivier Lorthioir, Catherine Ball, Vincenzo Garzya, Caroline Goodacre, Stephen Watson.   

Abstract

The identification of novel orally active mGluR5 antagonist GSK2210875 is described.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 21051228     DOI: 10.1016/j.bmcl.2010.09.120

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Recent advances in the design and development of novel negative allosteric modulators of mGlu(5).

Authors:  Kyle A Emmitte
Journal:  ACS Chem Neurosci       Date:  2011-08-17       Impact factor: 4.418

2.  The role of metabotropic glutamate receptor 5 on the stromal cell-derived factor-1/CXCR4 system in oral cancer.

Authors:  Nobuyuki Kuribayashi; Daisuke Uchida; Makoto Kinouchi; Natsumi Takamaru; Tetsuya Tamatani; Hirokazu Nagai; Youji Miyamoto
Journal:  PLoS One       Date:  2013-11-13       Impact factor: 3.240

  2 in total

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