Literature DB >> 21051201

Allograft (Alloderm) and autograft (temporalis fascia) implantation for glottic insufficiency: a novel approach.

Melin Tan1, Michael Bassiri-Tehrani, Peak Woo.   

Abstract

OBJECTIVE: Traditionally, glottic insufficiency because of scar, atrophy, and sulcus has been treated by injection or medialization laryngoplasty. These procedures do not reestablish the vertical height of the vocal fold margin. We propose soft tissue augmentation laryngoplasty with allograft (sheet Alloderm; LifeCell Corporation, Branchburg, NJ) or autograft (temporalis fascia) via a minithyrotomy or a transoral approach. STUDY
DESIGN: A retrospective case series analysis of 21 patients treated by sheet Alloderm or temporalis fascia for correction of glottic insufficiency.
METHODS: Twenty-one patients with glottic insufficiency secondary to scar, atrophy, or sulcus were treated. Ten failed prior techniques. Seventeen had minithyrotomy by a small fenestration in the thyroid cartilage. Exploration of scar or lamina propria through the fenestration allowed for the creation of a pocket for Alloderm implantation within the intermediate layer of the lamina propria. Four patients underwent a transoral approach by cordotomy with either Alloderm or temporalis fascia implantation, which also allowed for exploration of scar but required repair using sutures. These implantation approaches allowed for both restoration of the layered structure and augmentation of the middle third of the musculomembranous vocal fold. Preoperative and postoperative videostroboscopic examinations were reviewed with review of clinical outcome.
RESULTS: With a median follow-up time of 12 months, patients demonstrated excellent long-term vocal fold augmentation and minimal absorption of the implant in 19 out of 21 patients. There is improved pliability of the vocal fold with good oscillation in scar patients.
CONCLUSION: Minithyrotomy with soft tissue augmentation is a novel approach for soft tissue augmentation of glottic insufficiency. It has the advantage of augmentation of the medial edge of the vocal fold with a soft tissue implant that has long-term viability. Its role should be explored further in patients with atrophy and scar.
Copyright © 2011 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

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Year:  2010        PMID: 21051201     DOI: 10.1016/j.jvoice.2010.08.001

Source DB:  PubMed          Journal:  J Voice        ISSN: 0892-1997            Impact factor:   2.009


  2 in total

1.  Bilateral medialization thyroplasty in patients with vocal fold atrophy with or without sulcus.

Authors:  Emke M J M van den Broek; Bas J Heijnen; Martine Hendriksma; Vivienne A H van de Kamp-Lam; Thijs O Verhagen; Antonius P M Langeveld; Peter Paul G van Benthem; Elisabeth V Sjögren
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-04-02       Impact factor: 2.503

2.  Impact of patient-related factors on successful autologous fat injection laryngoplasty in thyroid surgical treated related unilateral vocal fold paralysis- observational study.

Authors:  Wen-Yang Lin; Wen-Dien Chang; Li-Wei Ko; Yung-An Tsou; Sheng-Hwa Chen
Journal:  Medicine (Baltimore)       Date:  2020-01       Impact factor: 1.817

  2 in total

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