Literature DB >> 21050240

Practice patterns for the evaluation and treatment of eosinophilic oesophagitis.

A F Peery1, N J Shaheen, E S Dellon.   

Abstract

BACKGROUND: Although consensus guidelines for eosinophilic oesophagitis have been published, it remains unclear whether gastroenterologists follow these recommendations. AIM: To assess academic and community practice patterns for the evaluation and treatment of eosinophilic oesophagitis and to compare these practices with current guidelines.
METHODS: This was a prospective study of academic and community gastroenterologists using a self-administered online survey.
RESULTS: A total of 60% (34 of 57) of academic and 29% (38 of 133) of community gastroenterologists completed the survey. Only 24% of academic and 3% of community gastroenterologists follow consensus guidelines to diagnose eosinophilic oesophagitis (P = 0.007). A proton pump inhibitor trial or negative pH study prior to diagnosis was required by just 25% of all gastroenterologists. A majority (60%) do not use the recommended threshold of 15 eosinophils per high powered field to diagnosis eosinophilic oesophagitis. Half (51%) mistakenly require a positive endoscopic finding. For first-line treatment, about half of the gastroenterologists surveyed treat with a swallowed topical steroid (53% academic, 56% community; P = N.S.), consistent with the guidelines.
CONCLUSIONS: There is variability in practice patterns for both diagnosis and treatment of eosinophilic oesophagitis. Ongoing education and research concerning diagnosis and treatment are needed.
© 2010 Blackwell Publishing Ltd.

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Year:  2010        PMID: 21050240      PMCID: PMC3099135          DOI: 10.1111/j.1365-2036.2010.04476.x

Source DB:  PubMed          Journal:  Aliment Pharmacol Ther        ISSN: 0269-2813            Impact factor:   8.171


  22 in total

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Review 3.  Non-surgical interventions for eosinophilic esophagitis.

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Journal:  Cochrane Database Syst Rev       Date:  2010-03-17

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Authors:  Shehzad Nawaz Merwat; Stuart Jon Spechler
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Review 6.  Potential anti-inflammatory effects of proton pump inhibitors: a review and discussion of the clinical implications.

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7.  Diagnosis of eosinophilic esophagitis after fundoplication for 'refractory reflux': implications for preoperative evaluation.

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Review 9.  Eosinophilic oesophagitis in adults.

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10.  Clinical, endoscopic, and histologic findings distinguish eosinophilic esophagitis from gastroesophageal reflux disease.

Authors:  Evan S Dellon; Wood B Gibbs; Karen J Fritchie; Tara C Rubinas; Lindsay A Wilson; John T Woosley; Nicholas J Shaheen
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  26 in total

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Review 2.  Role of Endoscopy in Diagnosis and Management of Pediatric Eosinophilic Esophagitis.

Authors:  Amanda B Muir; Jamie Merves; Chris A Liacouras
Journal:  Gastrointest Endosc Clin N Am       Date:  2016-01

3.  Prevalence of esophageal eosinophilia varies by climate zone in the United States.

Authors:  Jennifer M Hurrell; Robert M Genta; Evan S Dellon
Journal:  Am J Gastroenterol       Date:  2012-02-07       Impact factor: 10.864

4.  Clinical and Molecular Factors Associated With Histologic Response to Topical Steroid Treatment in Patients With Eosinophilic Esophagitis.

Authors:  Swathi Eluri; Sara R Selitsky; Irina Perjar; Johnathan Hollyfield; Renee Betancourt; Cara Randall; Spencer Rusin; John T Woosley; Nicholas J Shaheen; Evan S Dellon
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5.  Proton pump inhibitors therapy for esophageal eosinophilia: simply following consensus guidelines.

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Journal:  J Gastroenterol       Date:  2011-02-24       Impact factor: 7.527

6.  Management of eosinophilic esophagitis is often discordant with guidelines and not patient-centered: results of a survey of gastroenterologists.

Authors:  Joy W Chang; Sameer D Saini; Jessica L Mellinger; Joan W Chen; Brian J Zikmund-Fisher; Joel H Rubenstein
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7.  Development and Validation of a Mucosal Impedance Contour Analysis System to Distinguish Esophageal Disorders.

Authors:  Dhyanesh A Patel; Tina Higginbotham; James C Slaughter; Muhammad Aslam; Elif Yuksel; David Katzka; C Prakash Gyawali; Melina Mashi; John Pandolfino; Michael F Vaezi
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Review 8.  Diagnostics of eosinophilic esophagitis: clinical, endoscopic, and histologic pitfalls.

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Review 9.  Eosinophilic esophagitis.

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Review 10.  Eosinophilic esophagitis in adults: an update on medical management.

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