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Literature DB >> 21048797

Alzheimer disease: caspases first.

Jesús Avila.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2010 PMID： 21048797 DOI： 10.1038/nrneurol.2010.157

Source DB: PubMed Journal: Nat Rev Neurol ISSN： 1759-4758 Impact factor: 42.937

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10 in total

1. Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment.

Authors: R W Berry; A Abraha; S Lagalwar; N LaPointe; T C Gamblin; V L Cryns; L I Binder
Journal: Biochemistry Date: 2003-07-15 Impact factor: 3.162

2. Caspase activation precedes and leads to tangles.

Authors: Alix de Calignon; Leora M Fox; Rose Pitstick; George A Carlson; Brian J Bacskai; Tara L Spires-Jones; Bradley T Hyman
Journal: Nature Date: 2010-03-31 Impact factor: 49.962

3. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice.

Authors: J J Lucas; F Hernández; P Gómez-Ramos; M A Morán; R Hen; J Avila
Journal: EMBO J Date: 2001-01-15 Impact factor: 11.598

4. Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.

Authors: Angela L Guillozet-Bongaarts; Michael E Cahill; Vincent L Cryns; Matthew R Reynolds; Robert W Berry; Lester I Binder
Journal: J Neurochem Date: 2006-04-05 Impact factor: 5.372

5. Neurons may live for decades with neurofibrillary tangles.

Authors: R Morsch; W Simon; P D Coleman
Journal: J Neuropathol Exp Neurol Date: 1999-02 Impact factor: 3.685

6. Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease.

Authors: T Chris Gamblin; Feng Chen; Angara Zambrano; Aida Abraha; Sarita Lagalwar; Angela L Guillozet; Meiling Lu; Yifan Fu; Francisco Garcia-Sierra; Nichole LaPointe; Richard Miller; Robert W Berry; Lester I Binder; Vincent L Cryns
Journal: Proc Natl Acad Sci U S A Date: 2003-07-29 Impact factor: 11.205

7. Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy.

Authors: Patrice Delobel; Isabelle Lavenir; Graham Fraser; Esther Ingram; Max Holzer; Bernardino Ghetti; Maria Grazia Spillantini; R Anthony Crowther; Michel Goedert
Journal: Am J Pathol Date: 2007-12-13 Impact factor: 4.307

8. Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy.

Authors: Alix de Calignon; Tara L Spires-Jones; Rose Pitstick; George A Carlson; Bradley T Hyman
Journal: J Neuropathol Exp Neurol Date: 2009-07 Impact factor: 3.685

9. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.

Authors: Robert A Rissman; Wayne W Poon; Mathew Blurton-Jones; Salvatore Oddo; Reidun Torp; Michael P Vitek; Frank M LaFerla; Troy T Rohn; Carl W Cotman
Journal: J Clin Invest Date: 2004-07 Impact factor: 14.808

10. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.

Authors: P Cras; M A Smith; P L Richey; S L Siedlak; P Mulvihill; G Perry
Journal: Acta Neuropathol Date: 1995 Impact factor: 17.088

10 in total

14 in total

1. Does the cycad genotoxin MAM implicated in Guam ALS-PDC induce disease-relevant changes in mouse brain that includes olfaction?

Authors: Glen Kisby; Valerie Palmer; Mike Lasarev; Rebecca Fry; Mihail Iordanov; Eli Magun; Leona Samson; Peter Spencer
Journal: Commun Integr Biol Date: 2011-11-01

2. Tau and neuron aging.

Authors: Jesus Avila; Elena Gomez de Barreda; Noemi Pallas-Bazarra; Felix Hernandez
Journal: Aging Dis Date: 2012-12-03 Impact factor: 6.745

Review 3. The future of blood-based biomarkers for Alzheimer's disease.

Authors: Kim Henriksen; Sid E O'Bryant; Harald Hampel; John Q Trojanowski; Thomas J Montine; Andreas Jeromin; Kaj Blennow; Anders Lönneborg; Tony Wyss-Coray; Holly Soares; Chantal Bazenet; Magnus Sjögren; William Hu; Simon Lovestone; Morten A Karsdal; Michael W Weiner
Journal: Alzheimers Dement Date: 2013-07-11 Impact factor: 21.566

Alzheimer disease: caspases first.

1. Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment.

2. Caspase activation precedes and leads to tangles.

3. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice.

4. Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.

5. Neurons may live for decades with neurofibrillary tangles.

6. Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease.

7. Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy.

8. Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy.

9. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.

10. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.

1. Does the cycad genotoxin MAM implicated in Guam ALS-PDC induce disease-relevant changes in mouse brain that includes olfaction?

2. Tau and neuron aging.

Review 3. The future of blood-based biomarkers for Alzheimer's disease.

Review 4. Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention.

Review 5. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.

6. Induced tauopathy in a novel 3D-culture model mediates neurodegenerative processes: a real-time study on biochips.

Review 7. Interaction between α-synuclein and other proteins in neurodegenerative disorders.

8. Will posttranslational modifications of brain proteins provide novel serological markers for dementias?

Review 9. Interaction between pathogenic proteins in neurodegenerative disorders.

10. The involvement of cholinergic neurons in the spreading of tau pathology.