Literature DB >> 21048428

Extracellular matrix-derived peptides and myocardial repair.

Shirley S Mihardja1, Jiashing Yu, Randall J Lee.   

Abstract

Repairing cardiac tissue remains one of the most challenging goals in tissue engineering. Here, we discuss ways whereby we sought to treat myocardial infarctions using extracellular-matrix derived peptides. Using an ischemia/reperfusion myocardial infarction rodent model, we targeted these extracellular matrix-derived peptides to the myocardial infarct site and were able to induce angiogenesis and alter the negative remodeling seen after an acute myocardial infarction. Our results indicate a potentially new strategy for repairing damaged tissue.

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Year:  2011        PMID： 21048428      PMCID： PMC3084975          DOI： 10.4161/cam.5.2.13796

Source DB:  PubMed          Journal:  Cell Adh Migr        ISSN： 1933-6918            Impact factor:   3.405


  25 in total

1.  Type IV collagen modulates angiogenesis and neovessel survival in the rat aorta model.

Authors:  E Bonanno; M Iurlaro; J A Madri; R F Nicosia
Journal:  In Vitro Cell Dev Biol Anim       Date:  2000-05       Impact factor: 2.416

Review 2.  Extracellular matrix remodeling following myocardial injury.

Authors:  Merry L Lindsey; Douglas L Mann; Mark L Entman; Francis G Spinale
Journal:  Ann Med       Date:  2003       Impact factor: 4.709

3.  Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium.

Authors:  Karen L Christman; Andrew J Vardanian; Qizhi Fang; Richard E Sievers; Hubert H Fok; Randall J Lee
Journal:  J Am Coll Cardiol       Date:  2004-08-04       Impact factor: 24.094

Review 4.  Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?

Authors:  Bodh I Jugdutt
Journal:  Circulation       Date:  2003-09-16       Impact factor: 29.690

5.  Synthetic peptide with cell attachment activity of fibronectin.

Authors:  M Pierschbacher; E G Hayman; E Ruoslahti
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

6.  Worldwide thoracic organ transplantation: a report from the UNOS/ISHLT International Registry for Thoracic Organ Transplantation.

Authors:  B M Keck; L E Bennett; J Rosendale; O P Daily; R J Novick; J D Hosenpud
Journal:  Clin Transpl       Date:  1999

7.  The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.

Authors:  Jiashing Yu; Yiping Gu; Kim T Du; Shirley Mihardja; Richard E Sievers; Randall J Lee
Journal:  Biomaterials       Date:  2008-11-17       Impact factor: 12.479

8.  Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy.

Authors:  Jiashing Yu; Karen L Christman; Eric Chin; Richard E Sievers; Maythem Saeed; Randall J Lee
Journal:  J Thorac Cardiovasc Surg       Date:  2009-01       Impact factor: 5.209

9.  Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction.

Authors:  Karen L Christman; Hubert H Fok; Richard E Sievers; Qizhi Fang; Randall J Lee
Journal:  Tissue Eng       Date:  2004 Mar-Apr
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  1 in total

Review 1.  Left ventricular remodeling: one small step for the extracellular matrix will translate to a giant leap for the myocardium.

Authors:  Andriy Yabluchanskiy; Robert J Chilton; Merry L Lindsey
Journal:  Congest Heart Fail       Date:  2013-01-25
  1 in total

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