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Literature DB >> 21048353

Butyrolactones from the fungus Aspergillus terreus BCC 4651.

Rachada Haritakun¹, Pranee Rachtawee, Rungtiwa Chanthaket, Nattawut Boonyuen, Masahiko Isaka.

Abstract

Two new butenolides, butyrolactones VI (1) and VII (2), were isolated together with six known compounds, butyrolactones I (3), II (4), IV (5), and V (6), aspernolide B (7), and bisdethiodi(methylthio)acetylaranotin (8) from the fungus Aspergillus terreus BCC 4651. Compound 8, exhibiting a minimum inhibitory concentration (MIC) value of 1.56 µg/ml against Mycobacterium tuberculosis H37Ra, proved to be the antimycobacterial principle from the culture of this fungus. On the other hand, butyrolactone V (6) showed antiplasmodial activity against Plasmodium falciparum K1 with an IC₅₀ of 7.9 µg/ml.

Entities: Chemical Species

Mesh：

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Year: 2010 PMID： 21048353 DOI： 10.1248/cpb.58.1545

Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645

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Cited

11 in total

1. Bioactive compounds of Aspergillus terreus-F7, an endophytic fungus from Hyptis suaveolens (L.) Poit.

Authors: Igor Pereira da Silva; Elson Brissow; Luis Claudio Kellner Filho; Jaqueline Senabio; Kátia Aparecida de Siqueira; Samuel Vandresen Filho; Jaqueline Lopes Damasceno; Suzana Amorim Mendes; Denise Crispim Tavares; Lizandra Guidi Magalhães; Policarpo Ademar Sales Junior; Ana Helena Januário; Marcos Antônio Soares
Journal: World J Microbiol Biotechnol Date: 2017-02-27 Impact factor: 3.312

2. Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M^pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis.

Authors: Ibrahim S Uras; Michal Korinek; Amgad Albohy; Basma S Abdulrazik; Wenhan Lin; Sherif S Ebada; Belma Konuklugil
Journal: ChemistrySelect Date: 2022-03-28 Impact factor: 2.307

3. Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis.

Authors: Chun-Jun Guo; Hsu-Hua Yeh; Yi-Ming Chiang; James F Sanchez; Shu-Ling Chang; Kenneth S Bruno; Clay C C Wang
Journal: J Am Chem Soc Date: 2013-05-01 Impact factor: 15.419

4. Four butyrolactones and diverse bioactive secondary metabolites from terrestrial Aspergillus flavipes MM2: isolation and structure determination.

Authors: Mohamed Ms Nagia; Mohammad Magdy El-Metwally; Mohamed Shaaban; Soheir M El-Zalabani; Atef G Hanna
Journal: Org Med Chem Lett Date: 2012-03-01

Butyrolactones from the fungus Aspergillus terreus BCC 4651.

1. Bioactive compounds of Aspergillus terreus-F7, an endophytic fungus from Hyptis suaveolens (L.) Poit.

2. Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (M^pro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis.

3. Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis.

4. Four butyrolactones and diverse bioactive secondary metabolites from terrestrial Aspergillus flavipes MM2: isolation and structure determination.

5. Territrem and butyrolactone derivatives from a marine-derived fungus Aspergillus terreus.

6. Open-Ring Butenolides from a Marine-Derived Anti-Neuroinflammatory Fungus Aspergillus terreus Y10.

7. Synthesis of novel phytol-derived γ-butyrolactones and evaluation of their biological activity.

8. In silico prediction of natural compounds as potential multi-target inhibitors of structural proteins of SARS-CoV-2.

9. Diverse Secondary Metabolites from the Coral-Derived Fungus Aspergillus hiratsukae SCSIO 5Bn₁003.

10. Butenolides from the Coral-Derived Fungus Aspergillius terreus SCSIO41404.