Literature DB >> 21046135

Anticholinergic therapy: do the patients take the pills prescribed?

Katharina Jundt1, Kathrin Schreyer, Klaus Friese, Ursula Peschers.   

Abstract

PURPOSE: To evaluate how many patients with overactive bladder still take their prescribed medication at least 12 months later and to find out the reasons for discontinuation of the therapy.
METHODS: Two hundred and ten patients who had received a prescription for anticholinergic medication were contacted by telephone 12-46 months later.
RESULTS: Out of 210 eligible patients 132 (63%) could be contacted and gave consent to participate in the study. 38% of them still took their medication after at least 12 months. 17% were continent or much improved, 13% a little improved, 8% were not improved, although still taking their medication. 62% did not take the original medication any more. 10% had never started with the medication, 42% took the medication for 3 months and 8% for 4-12 months. 25% had changed to another anticholinergic drug.
CONCLUSION: Anticholinergic therapy is often discontinued by patients and doctors. Patients with OAB therefore need counselling and follow-up in the long term to make sure that alternative treatment is offered if anticholinergic treatment does not work.

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Year:  2010        PMID: 21046135     DOI: 10.1007/s00404-010-1720-x

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  8 in total

1.  Efficacy of Transcutaneous Electrical Nerve Stimulation in the Treatment of Overactive Bladder.

Authors:  Nidhi Sharma; Kaja Rekha; Krishnamurthy Jayashree Srinivasan
Journal:  J Clin Diagn Res       Date:  2016-10-01

Review 2.  The effect of onabotulinumtoxinA according to site of injection in patients with overactive bladder: a systematic review and meta-analysis.

Authors:  Jung Ki Jo; Kyu Nam Kim; Dong Won Kim; Yong Tae Kim; Ji Yoon Kim; Ji Yeon Kim
Journal:  World J Urol       Date:  2017-11-09       Impact factor: 4.226

Review 3.  Refractory overactive bladder: a common problem?

Authors:  Ulrich Schwantes; Joachim Grosse; Andreas Wiedemann
Journal:  Int Urogynecol J       Date:  2015-03-20       Impact factor: 2.894

4.  Impact of mirabegron extended-release on the treatment of overactive bladder with urge urinary incontinence, urgency, and frequency.

Authors:  Raymond T Lee; Mitchell Bamberger; Pamela Ellsworth
Journal:  Res Rep Urol       Date:  2013-10-25

Review 5.  Medication adherence in the management of nocturia: challenges and solutions.

Authors:  Ravishankar Jayadevappa; Diane K Newman; Sumedha Chhatre; Alan J Wein
Journal:  Patient Prefer Adherence       Date:  2015-01-13       Impact factor: 2.711

Review 6.  OnabotulinumtoxinA for neurogenic detrusor overactivity and dose differences: a systematic review.

Authors:  Rui Zhang; Yongteng Xu; Shengping Yang; Hui Liang; Yunxin Zhang; Yali Liu
Journal:  Int Braz J Urol       Date:  2015 Mar-Apr       Impact factor: 1.541

Review 7.  Efficacy and Safety of OnabotulinumtoxinA in Patients with Neurogenic Detrusor Overactivity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Authors:  Tao Cheng; Wei-Bing Shuang; Dong-Dong Jia; Min Zhang; Xu-Nan Tong; Wei-Dong Yang; Xu-Ming Jia; Shuo Li
Journal:  PLoS One       Date:  2016-07-27       Impact factor: 3.240

8.  A systematic review and meta-analysis of effectiveness and safety of therapy for overactive bladder using botulinum toxin A at different dosages.

Authors:  Hui-Yun Gu; Ju-Kun Song; Wen-Jun Zhang; Jin Xie; Qi-Sheng Yao; Wen-Jing Zeng; Chao Zhang; Yu-Ming Niu
Journal:  Oncotarget       Date:  2017-08-07
  8 in total

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