Literature DB >> 21045506

Gabapentin as a rescue drug in D-penicillamine-induced status dystonicus in patients with Wilson disease.

Vimal K Paliwal1, Pankaj K Gupta, Sunil Pradhan.   

Abstract

D-penicillamine induced status dystonicus is a unique but serious drug related complication in a subset of patients with Wilson disease. Patho-physiological basis of its occurrence is not known. It often responds poorly to anti dystonia medications. We present three patients with Wilson disease who developed severe paroxysmal dystonic spells after receiving D-penicillamine treatment. All three patients responded well to gabapentin after failing to respond to other anti dystonia drugs.

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Year:  2010        PMID: 21045506     DOI: 10.4103/0028-3886.72184

Source DB:  PubMed          Journal:  Neurol India        ISSN: 0028-3886            Impact factor:   2.117


  8 in total

1.  Difficulties in diagnosis and treatment of Wilson disease-a case series of five patients.

Authors:  Anna Członkowska; Karolina Dzieżyc-Jaworska; Bożena Kłysz; Rędzia-Ogrodnik Barbara; Tomasz Litwin
Journal:  Ann Transl Med       Date:  2019-04

2.  Treatment of generalized dystonia.

Authors:  Naomi Lubarr; Susan Bressman
Journal:  Curr Treat Options Neurol       Date:  2011-06       Impact factor: 3.598

3.  Pediatric Dystonic Storm: A Hospital-Based Study.

Authors:  Jyotindra Narayan Goswami; Shuvendu Roy; Saroj Kumar Patnaik
Journal:  Neurol Clin Pract       Date:  2021-10

4.  Status Dystonicus as an Acute Sequelae Following Anoxic Cerebral Damage.

Authors:  Somdattaa Ray; Ravinder Jeet Singh Sidhu; Pramod Kumar Pal; Ravi Yadav
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2019-04-15

Review 5.  The Pragmatic Treatment of Wilson's Disease.

Authors:  Annu Aggarwal; Mohit Bhatt
Journal:  Mov Disord Clin Pract       Date:  2014-04-10

Review 6.  Dystonic storm: a practical clinical and video review.

Authors:  Pichet Termsarasab; Steven J Frucht
Journal:  J Clin Mov Disord       Date:  2017-04-28

Review 7.  A Proposed Diagnostic Algorithm for Inborn Errors of Metabolism Presenting With Movements Disorders.

Authors:  Juan Darío Ortigoza-Escobar
Journal:  Front Neurol       Date:  2020-11-13       Impact factor: 4.003

8.  Advance in the pathogenesis and treatment of Wilson disease.

Authors:  Qin-Yun Dong; Zhi-Ying Wu
Journal:  Transl Neurodegener       Date:  2012-11-27       Impact factor: 8.014

  8 in total

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