Literature DB >> 21045287

Structure of Plasmodium falciparum ADP-ribosylation factor 1.

William J Cook1, Craig D Smith, Olga Senkovich, Anthony A Holder, Debasish Chattopadhyay.   

Abstract

Vesicular trafficking may play a crucial role in the pathogenesis and survival of the malaria parasite. ADP-ribosylation factors (ARFs) are among the major components of vesicular trafficking pathways in eukaryotes. The crystal structure of ARF1 GTPase from Plasmodium falciparum has been determined in the GDP-bound conformation at 2.5 Å resolution and is compared with the structures of mammalian ARF1s.

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Year:  2010        PMID： 21045287      PMCID： PMC3001640          DOI： 10.1107/S1744309110036997

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


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