Literature DB >> 21043493

Palladium-catalyzed benzylic arylation of 2-methyl azaarenes.

Paul M Burton1, James A Morris.   

Abstract

A palladium-catalyzed benzylic sp(3) direct arylation of electron-deficient heterocycles is reported. The method described enables the introduction of electron-rich and -poor aromatics at the benzylic position of heterocycles without the need for preactivation or the use of directing groups.

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Year:  2010        PMID: 21043493     DOI: 10.1021/ol102276e

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  Palladium-Catalyzed Triarylation of sp3 C-H Bonds in Heteroarylmethanes: Synthesis of Triaryl(heteroaryl)methanes.

Authors:  Shuguang Zhang; Bowen Hu; Zhipeng Zheng; Patrick J Walsh
Journal:  Adv Synth Catal       Date:  2018-02-03       Impact factor: 5.837

2.  Palladium-Catalyzed Benzylic C-H Arylation of Azaarylmethylamines.

Authors:  Byeong-Seon Kim; Jacqueline Jiménez; Feng Gao; Patrick J Walsh
Journal:  Org Lett       Date:  2015-11-17       Impact factor: 6.005

3.  Chemo- and regioselective C(sp³)-H arylation of unactivated allylarenes by deprotonative cross-coupling.

Authors:  Nusrah Hussain; Gustavo Frensch; Jiadi Zhang; Patrick J Walsh
Journal:  Angew Chem Int Ed Engl       Date:  2014-02-26       Impact factor: 15.336

4.  Palladium-Catalyzed Benzylic Arylation of Pyridylmethyl Silyl Ethers: One-Pot Synthesis of Aryl(pyridyl)methanols.

Authors:  Alexandra R Rivero; Byeong-Seon Kim; Patrick J Walsh
Journal:  Org Lett       Date:  2016-03-23       Impact factor: 6.005

5.  Chemoselective Palladium-Catalyzed Deprotonative Arylation/[1,2]-Wittig Rearrangement of Pyridylmethyl Ethers.

Authors:  Feng Gao; Byeong-Seon Kim; Patrick J Walsh
Journal:  Chem Sci       Date:  2015-10-27       Impact factor: 9.825

6.  Palladium-catalysed synthesis of triaryl(heteroaryl)methanes.

Authors:  Shuguang Zhang; Byeong-Seon Kim; Chen Wu; Jianyou Mao; Patrick J Walsh
Journal:  Nat Commun       Date:  2017-03-14       Impact factor: 14.919

7.  Lewis Basic Salt-Promoted Organosilane Coupling Reactions with Aromatic Electrophiles.

Authors:  Tyler W Reidl; Jeffrey S Bandar
Journal:  J Am Chem Soc       Date:  2021-07-27       Impact factor: 16.383

  7 in total

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