| Literature DB >> 21041504 |
María-José Ferrándiz1, Carmen Ardanuy, Josefina Liñares, Luz Balsalobre, María Teresa García, Adela G de la Campa.
Abstract
Eight rifampin-resistant streptococci of the mitis group were identified at the species level by using a concatenated 16S rRNA gene-sodA-rpoB-hlpA sequence. Characterization of their rpoB alleles showed single amino acid changes involved in rifampin resistance. Comparison of RpoB sequences from pneumococcal recombinant isolates, viridans isolates, and type strains revealed a species-specific amino acid signature, which allowed it to be ascertained that recombinant RpoBs were originated in genetic interchanges with Streptococcus mitis and Streptococcus oralis.Entities:
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Year: 2010 PMID: 21041504 PMCID: PMC3019657 DOI: 10.1128/AAC.00856-10
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191