Literature DB >> 21040990

Intensity modulated radiosurgery for the spine: dosimetric impact of beamlet size variation in the leaf travel direction.

Joo Young Kim1, Hyun Soo Shin, Ja Young Kim, Hyeli Park, Sung Joon Kim.   

Abstract

BACKGROUND AND
PURPOSE: To investigate the dosimetric impact of beamlet size in the leaf travel direction for the spinal treatment using intensity-modulated radiosurgery (IMRS).
MATERIALS AND METHODS: The IMRS plans of ten patients (11 lesions - 6 thoracic, 2 cervical, 3 lumbar) were re-planned using four different beamlet sizes (1, 2, 5, and 10 mm) - in the leaf travel direction, while keeping the Y-dimension by multi-leaf collimator (MLC) width fixed, and compared to the reference plan with beamlet size of 3 mm. To evaluate the beamlet size effect, target volumes (coverage, conformity, and size effect), organ at risks (OARS) (doses to the spinal cord, lung and kidneys), and integral dose, and monitor units (MUs) were calculated.
RESULTS: Target coverage and dose conformity for planning target volume (PTV) were not correlated with beamlet size. Maximum (p=0.000) and mean (p=0.000) spinal cord doses decreased by 4.0% and 3.4% from 23.4% and 28.6% as beamlet size decreased from 10 to 1 mm. The integral doses, MUs and doses to other organs increased at smaller beamlet sizes. MUs for a beamlet size of 10 mm decreased by 31.4%, as compared with that at the reference beamlet size.
CONCLUSIONS: Despite no dosimetric benefits with respect to target volume and an MU increase, a definite dose reduction was observed at the spinal cord for smaller beamlet sizes. Treatment with IMRS planning for the spine will benefit from the use of a beamlet size between 2 and 4 mm.
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 21040990     DOI: 10.1016/j.radonc.2010.10.001

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  2 in total

1.  Dose Evaluation of Fractionated Schema and Distance From Tumor to Spinal Cord for Spinal SBRT with Simultaneous Integrated Boost: A Preliminary Study.

Authors:  Hao Yang; Bo-ning Cai; Xiao-shen Wang; Xiao-hu Cong; Wei Xu; Jin-yuan Wang; Jun Yang; Shou-ping Xu; Zhong-jian Ju; Lin Ma
Journal:  Med Sci Monit       Date:  2016-02-23

2.  Influence of beamlet width on dynamic IMRT plan quality in nasopharyngeal carcinoma.

Authors:  Manya Wu; Jinhui Jin; Zhenghuan Li; Fantu Kong; Yadi He; Lijiang Liu; Wei Yang; Xiangying Xu
Journal:  PeerJ       Date:  2022-08-05       Impact factor: 3.061

  2 in total

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