| Literature DB >> 21040834 |
Annelies Quaegebeur1, Inmaculada Segura, Peter Carmeliet.
Abstract
The role of pericytes in the control of blood-brain barrier (BBB) integrity has remained enigmatic. In this issue, Bell et al. and two concurrent studies highlight that pericyte loss causes BBB breakdown and hypoperfusion. Remarkably, these vascular changes precede neurodegeneration and cognitive defects in old age.Entities:
Year: 2010 PMID: 21040834 DOI: 10.1016/j.neuron.2010.10.024
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173