Literature DB >> 21039144

What happens to Modic changes following lumbar discectomy? Analysis of a cohort of 41 patients with a 3- to 5-year follow-up period.

Ralph Rahme1, Ronald Moussa, Rabih Bou-Nassif, Joseph Maarrawi, Tony Rizk, Georges Nohra, Elie Samaha, Nabil Okais.   

Abstract

OBJECT: The natural history of Modic changes (MCs) in the lumbar spine is often marked by conversion from one type to another, but their course following lumbar discectomy remains unknown. The authors sought to study the impact of surgery on the natural history of these lesions.
METHODS: Forty-one patients treated with lumbar microdiscectomy between 2004 and 2005 were enrolled in this study and underwent clinical evaluation and repeat MR imaging after a median follow-up of 41 months (range 32-59 months). Preoperative and follow-up MR images were reviewed and the type, location, and extent of MCs at the operated level were recorded and compared.
RESULTS: The study population consisted of 27 men and 14 women with a mean age of 54 years (range 24-78 years). During the follow-up period, the prevalence of MCs increased from 46.3% to 78%, and 26 patients (63.4%) had Type 2 lesions at the operated level. Of the 22 patients without MCs, 4 (18.2%) converted to Type 1 and 9 (40.9%) to Type 2. Of the 5 Type 1 lesions, 3 (60%) converted to Type 2, and 2 (40%) remained Type 1 but increased in size. In contrast, none of the 14 Type 2 changes converted to another type, although 10 (71.4%) increased in extent. There were no reverse conversions to Type 0.
CONCLUSIONS: Following lumbar discectomy, most patients develop Type 2 changes at the operated level, possibly as a result of accelerated degeneration in the operated disc. Neither the preoperative presence of MCs nor their postoperative course appears to affect the clinical outcome.

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Year:  2010        PMID: 21039144     DOI: 10.3171/2010.5.SPINE09818

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  15 in total

1.  Endplate changes following discectomy: natural history and associations between imaging and clinical data.

Authors:  Bradley K Weiner; Milorad Vilendecic; Darko Ledic; Sandro Eustacchio; Peter Varga; Miro Gorensek; Joseph Fernandez-Moure; John A Hipp
Journal:  Eur Spine J       Date:  2014-12-28       Impact factor: 3.134

Review 2.  Do Modic changes have an impact on clinical outcome in lumbar spine surgery? A systematic literature review.

Authors:  Aske Foldbjerg Laustsen; Rachid Bech-Azeddine
Journal:  Eur Spine J       Date:  2016-05-13       Impact factor: 3.134

3.  The effects of lumbar fusion and non-fusion surgery on the development of Modic changes.

Authors:  Xiaoping Mu; Seong Woong Kim; Eberhard Uhl; Karsten Schöller
Journal:  J Orthop Surg Res       Date:  2022-07-01       Impact factor: 2.677

4.  Effect of a strutted intradiscal spacer (DIVA®) on disc reherniation following lumbar discectomy: A 2-year retrospective matched cohort study.

Authors:  Robin Srour; Amira El Arbi; Ahmed Rahmouni; Hani Aljohani; Daniel Orenstein; Xavier Hoarau; Mustapha Ali Benali; Jihad Mortada; François Sellal
Journal:  J Orthop       Date:  2021-05-07

5.  Does disk space degeneration according to Los Angeles and Modic scales have relation with recurrent disk herniation?

Authors:  Saied Abrishamkar; Mehdi Mahmoudkhani; Bahram Aminmansour; Amir Mahabadi; Shohreh Jafari
Journal:  Adv Biomed Res       Date:  2014-11-20

6.  Semi-quantitative evaluation of signal intensity and contrast-enhancement in Modic changes.

Authors:  Marta Tibiletti; Cristina Ciavarro; Vlasta Bari; Iain W McCall; Jill P G Urban; Marco Brayda-Bruno; Fabio Galbusera
Journal:  Eur Radiol Exp       Date:  2017-06-29

7.  Association of Modic change types and their short tau inversion recovery signals with clinical characteristics- a cross sectional study of chronic low back pain patients in the AIM-study.

Authors:  Lars Christian Haugli Bråten; Elina Iordanova Schistad; Ansgar Espeland; Per Martin Kristoffersen; Anne Julsrud Haugen; Gunn Hege Marchand; Nils Vetti; Are Hugo Pripp; Thomas Istvan Kadar; Jan Sture Skouen; Margreth Grotle; Lars Grøvle; John-Anker Zwart; Jens Ivar Brox; Kjersti Storheim
Journal:  BMC Musculoskelet Disord       Date:  2020-06-10       Impact factor: 2.362

8.  No effect of 6-month intake of glucosamine sulfate on Modic changes or high intensity zones in the lumbar spine: sub-group analysis of a randomized controlled trial.

Authors:  Philip Wilkens; Kjersti Storheim; Inger Scheel; Linda Berg; Ansgar Espeland
Journal:  J Negat Results Biomed       Date:  2012-08-17

9.  Late appearance of low back pain relating to Modic change after lumbar discectomy.

Authors:  Keyvan Mostofi; Babak Gharaei Moghaddam; Morad Peyravi
Journal:  J Craniovertebr Junction Spine       Date:  2018 Apr-Jun

10.  Recurrent lumbar disc herniation recurrence after percutaneous endoscopic lumbar discectomy: A case report.

Authors:  Yuanyi Wang; Cong Ning; Feng Xu; Yipeng Xiang; Liyu Yao; Yadong Liu; Wenjing Zhang; Xiuying Huang; Changfeng Fu
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.817

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