Literature DB >> 21036612

1,2,3-triazolyl amino acids as AMPA receptor ligands.

N J Stanley1, D Sejer Pedersen, B Nielsen, T Kvist, J M Mathiesen, H Bräuner-Osborne, D K Taylor, A D Abell.   

Abstract

The central nervous system glutamate receptors are an important target for drug discovery. Herein we report initial investigations into the synthesis and glutamate receptor activity of 1,2,3-triazolyl amino acids. Two compounds were found to be selective AMPA receptor ligands, which warrant further investigation.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 21036612     DOI: 10.1016/j.bmcl.2010.09.139

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

1.  Impact of the Histidine-Triazole and Tryptophan-Pyrene Exchange in the WHW Peptide: Cu(II) Binding, DNA/RNA Interactions and Bioactivity.

Authors:  Ivona Krošl; Marta Košćak; Karla Ribičić; Biserka Žinić; Dragomira Majhen; Ksenija Božinović; Ivo Piantanida
Journal:  Int J Mol Sci       Date:  2022-06-23       Impact factor: 6.208

Review 2.  Tailored therapeutics based on 1,2,3-1H-triazoles: a mini review.

Authors:  Parteek Prasher; Mousmee Sharma
Journal:  Medchemcomm       Date:  2019-05-14       Impact factor: 3.597

3.  Optimized syntheses of Fmoc azido amino acids for the preparation of azidopeptides.

Authors:  Jan Pícha; Miloš Buděšínský; Kateřina Macháčková; Michaela Collinsová; Jiří Jiráček
Journal:  J Pept Sci       Date:  2017-01-25       Impact factor: 1.905

Review 4.  1,2,3-Triazoles as Biomimetics in Peptide Science.

Authors:  Naima Agouram; El Mestafa El Hadrami; Abdeslem Bentama
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411

  4 in total

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