| Literature DB >> 21035497 |
Meena Jhanwar-Uniyal1, Ladislau Albert, Elise McKenna, Michael Karsy, Priya Rajdev, Alex Braun, Raj Murali.
Abstract
These findings emphasize that the mTOR pathway may contribute to maintenance of quiescence of CSCs, and provide a basis for manipulating CSCs in the treatment of GBM. Future research should focus on further defining the PI3K/Akt/mTOR molecular network in the regulation of stem cell quiescence and provide rationale for targeting the cancer-initiating cells of GBM.Entities:
Mesh：
Substances：
Year: 2010 PMID： 21035497 DOI： 10.1016/j.advenzreg.2010.09.017
Source DB: PubMed Journal: Adv Enzyme Regul ISSN： 0065-2571