BACKGROUND: It is not clear if there is a difference in prognosis between male breast cancer (MBC) and female breast cancer (FBC) patients. The aim of this study was to compare the prognosis of MBC and FBC patients in China and the prognosis of MBC and their corresponding postmenopausal FBC patients. METHODS: Thirty-five MBC patients who were treated at the Sun Yat-sen University Cancer Center between 1969 and 2004 were enrolled in the study. Seventy FBC patients who were matched with the MBC patients for TNM stage, year of diagnosis, and age at diagnosis were simultaneously enrolled in the study. A second group comprising 18 MBC patients and their corresponding 36 matched postmenopausal FBC patients were also enrolled. The whole group and the postmenopausal groups were compared for five- and ten-year survivals. RESULTS: All the factors that could potentially affect prognosis were comparable among the groups except more FBC than MBC patients underwent endocrine therapy and a modified radical mastectomy. The 5- and 10-year survivals in the whole group were 81.6% and 60.3% for men and 90.7% and 73.5% for women (P = 0.02). The 5- and 10-year survival in the postmenopausal group was 82.5% and 100% for men and 66.0% and 85.9% for women (P = 0.159). CONCLUSIONS: Chinese FBC patients had a better prognosis than Chinese MBC patients. However, MBC patients and their corresponding postmenopausal FBC patients had a similar prognosis.
BACKGROUND: It is not clear if there is a difference in prognosis between male breast cancer (MBC) and female breast cancer (FBC) patients. The aim of this study was to compare the prognosis of MBC and FBC patients in China and the prognosis of MBC and their corresponding postmenopausal FBC patients. METHODS: Thirty-five MBCpatients who were treated at the Sun Yat-sen University Cancer Center between 1969 and 2004 were enrolled in the study. Seventy FBC patients who were matched with the MBCpatients for TNM stage, year of diagnosis, and age at diagnosis were simultaneously enrolled in the study. A second group comprising 18 MBCpatients and their corresponding 36 matched postmenopausal FBC patients were also enrolled. The whole group and the postmenopausal groups were compared for five- and ten-year survivals. RESULTS: All the factors that could potentially affect prognosis were comparable among the groups except more FBC than MBCpatients underwent endocrine therapy and a modified radical mastectomy. The 5- and 10-year survivals in the whole group were 81.6% and 60.3% for men and 90.7% and 73.5% for women (P = 0.02). The 5- and 10-year survival in the postmenopausal group was 82.5% and 100% for men and 66.0% and 85.9% for women (P = 0.159). CONCLUSIONS: Chinese FBC patients had a better prognosis than Chinese MBCpatients. However, MBCpatients and their corresponding postmenopausal FBC patients had a similar prognosis.
Authors: Luiz Claudio Santos Thuler; Anke Bergmann; Paulo Franscisco Mascarenhas Bender; Letícia Lima de Oliveira; Célia Regina Costa; Suzana Sales de Aguiar Journal: J Cancer Res Clin Oncol Date: 2017-06-15 Impact factor: 4.553
Authors: Paulo Franscisco Mascarenhas Bender; Letícia Lima de Oliveira; Célia Regina Costa; Suzana Sales de Aguiar; Anke Bergmann; Luiz Claudio Santos Thuler Journal: J Cancer Res Clin Oncol Date: 2016-12-08 Impact factor: 4.553