Literature DB >> 21030986

Accelerating the pulse of cardiovascular R&D.

Andrew Plump1.   

Abstract

Renewed commitment to cardiovascular drug development is needed to combat what is likely to be the leading cause of death for the next two decades. How might this be achieved?

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Mesh：

Year:  2010        PMID： 21030986     DOI： 10.1038/nrd3315

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  6 in total

1.  Prevalence of diabetes among men and women in China.

Authors:  Wenying Yang; Juming Lu; Jianping Weng; Weiping Jia; Linong Ji; Jianzhong Xiao; Zhongyan Shan; Jie Liu; Haoming Tian; Qiuhe Ji; Dalong Zhu; Jiapu Ge; Lixiang Lin; Li Chen; Xiaohui Guo; Zhigang Zhao; Qiang Li; Zhiguang Zhou; Guangliang Shan; Jiang He
Journal:  N Engl J Med       Date:  2010-03-25       Impact factor: 91.245

2.  An uncertain future for cardiovascular drug development?

Authors:  Alan M Garber
Journal:  N Engl J Med       Date:  2009-03-19       Impact factor: 91.245

3.  Aldosterone synthase inhibition with LCI699: a proof-of-concept study in patients with primary aldosteronism.

Authors:  Laurence Amar; Michel Azizi; Joël Menard; Séverine Peyrard; Catherine Watson; Pierre-François Plouin
Journal:  Hypertension       Date:  2010-09-13       Impact factor: 10.190

4.  Dabigatran versus warfarin in patients with atrial fibrillation.

Authors:  Stuart J Connolly; Michael D Ezekowitz; Salim Yusuf; John Eikelboom; Jonas Oldgren; Amit Parekh; Janice Pogue; Paul A Reilly; Ellison Themeles; Jeanne Varrone; Susan Wang; Marco Alings; Denis Xavier; Jun Zhu; Rafael Diaz; Basil S Lewis; Harald Darius; Hans-Christoph Diener; Campbell D Joyner; Lars Wallentin
Journal:  N Engl J Med       Date:  2009-08-30       Impact factor: 91.245

5.  Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research.

Authors:  David A Calhoun; Daniel Jones; Stephen Textor; David C Goff; Timothy P Murphy; Robert D Toto; Anthony White; William C Cushman; William White; Domenic Sica; Keith Ferdinand; Thomas D Giles; Bonita Falkner; Robert M Carey
Journal:  Hypertension       Date:  2008-04-07       Impact factor: 10.190

6.  Biological, clinical and population relevance of 95 loci for blood lipids.

Authors:  Tanya M Teslovich; Kiran Musunuru; Albert V Smith; Andrew C Edmondson; Ioannis M Stylianou; Masahiro Koseki; James P Pirruccello; Samuli Ripatti; Daniel I Chasman; Cristen J Willer; Christopher T Johansen; Sigrid W Fouchier; Aaron Isaacs; Gina M Peloso; Maja Barbalic; Sally L Ricketts; Joshua C Bis; Yurii S Aulchenko; Gudmar Thorleifsson; Mary F Feitosa; John Chambers; Marju Orho-Melander; Olle Melander; Toby Johnson; Xiaohui Li; Xiuqing Guo; Mingyao Li; Yoon Shin Cho; Min Jin Go; Young Jin Kim; Jong-Young Lee; Taesung Park; Kyunga Kim; Xueling Sim; Rick Twee-Hee Ong; Damien C Croteau-Chonka; Leslie A Lange; Joshua D Smith; Kijoung Song; Jing Hua Zhao; Xin Yuan; Jian'an Luan; Claudia Lamina; Andreas Ziegler; Weihua Zhang; Robert Y L Zee; Alan F Wright; Jacqueline C M Witteman; James F Wilson; Gonneke Willemsen; H-Erich Wichmann; John B Whitfield; Dawn M Waterworth; Nicholas J Wareham; Gérard Waeber; Peter Vollenweider; Benjamin F Voight; Veronique Vitart; Andre G Uitterlinden; Manuela Uda; Jaakko Tuomilehto; John R Thompson; Toshiko Tanaka; Ida Surakka; Heather M Stringham; Tim D Spector; Nicole Soranzo; Johannes H Smit; Juha Sinisalo; Kaisa Silander; Eric J G Sijbrands; Angelo Scuteri; James Scott; David Schlessinger; Serena Sanna; Veikko Salomaa; Juha Saharinen; Chiara Sabatti; Aimo Ruokonen; Igor Rudan; Lynda M Rose; Robert Roberts; Mark Rieder; Bruce M Psaty; Peter P Pramstaller; Irene Pichler; Markus Perola; Brenda W J H Penninx; Nancy L Pedersen; Cristian Pattaro; Alex N Parker; Guillaume Pare; Ben A Oostra; Christopher J O'Donnell; Markku S Nieminen; Deborah A Nickerson; Grant W Montgomery; Thomas Meitinger; Ruth McPherson; Mark I McCarthy; Wendy McArdle; David Masson; Nicholas G Martin; Fabio Marroni; Massimo Mangino; Patrik K E Magnusson; Gavin Lucas; Robert Luben; Ruth J F Loos; Marja-Liisa Lokki; Guillaume Lettre; Claudia Langenberg; Lenore J Launer; Edward G Lakatta; Reijo Laaksonen; Kirsten O Kyvik; Florian Kronenberg; Inke R König; Kay-Tee Khaw; Jaakko Kaprio; Lee M Kaplan; Asa Johansson; Marjo-Riitta Jarvelin; A Cecile J W Janssens; Erik Ingelsson; Wilmar Igl; G Kees Hovingh; Jouke-Jan Hottenga; Albert Hofman; Andrew A Hicks; Christian Hengstenberg; Iris M Heid; Caroline Hayward; Aki S Havulinna; Nicholas D Hastie; Tamara B Harris; Talin Haritunians; Alistair S Hall; Ulf Gyllensten; Candace Guiducci; Leif C Groop; Elena Gonzalez; Christian Gieger; Nelson B Freimer; Luigi Ferrucci; Jeanette Erdmann; Paul Elliott; Kenechi G Ejebe; Angela Döring; Anna F Dominiczak; Serkalem Demissie; Panagiotis Deloukas; Eco J C de Geus; Ulf de Faire; Gabriel Crawford; Francis S Collins; Yii-der I Chen; Mark J Caulfield; Harry Campbell; Noel P Burtt; Lori L Bonnycastle; Dorret I Boomsma; S Matthijs Boekholdt; Richard N Bergman; Inês Barroso; Stefania Bandinelli; Christie M Ballantyne; Themistocles L Assimes; Thomas Quertermous; David Altshuler; Mark Seielstad; Tien Y Wong; E-Shyong Tai; Alan B Feranil; Christopher W Kuzawa; Linda S Adair; Herman A Taylor; Ingrid B Borecki; Stacey B Gabriel; James G Wilson; Hilma Holm; Unnur Thorsteinsdottir; Vilmundur Gudnason; Ronald M Krauss; Karen L Mohlke; Jose M Ordovas; Patricia B Munroe; Jaspal S Kooner; Alan R Tall; Robert A Hegele; John J P Kastelein; Eric E Schadt; Jerome I Rotter; Eric Boerwinkle; David P Strachan; Vincent Mooser; Kari Stefansson; Muredach P Reilly; Nilesh J Samani; Heribert Schunkert; L Adrienne Cupples; Manjinder S Sandhu; Paul M Ridker; Daniel J Rader; Cornelia M van Duijn; Leena Peltonen; Gonçalo R Abecasis; Michael Boehnke; Sekar Kathiresan
Journal:  Nature       Date:  2010-08-05       Impact factor: 49.962
  6 in total
  6 in total

1.  Purinergic receptors in the carotid body as a new drug target for controlling hypertension.

Authors:  Wioletta Pijacka; Davi J A Moraes; Laura E K Ratcliffe; Angus K Nightingale; Emma C Hart; Melina P da Silva; Benedito H Machado; Fiona D McBryde; Ana P Abdala; Anthony P Ford; Julian F R Paton
Journal:  Nat Med       Date:  2016-09-05       Impact factor: 53.440

2.  Blunted sympathoinhibitory responses in obesity-related hypertension are due to aberrant central but not peripheral signalling mechanisms.

Authors:  Jackie M Y How; Suhail A Wardak; Shaik I Ameer; Rachel A Davey; Daniela M Sartor
Journal:  J Physiol       Date:  2014-02-03       Impact factor: 5.182

3.  Insights from systems pharmacology into cardiovascular drug discovery and therapy.

Authors:  Peng Li; Yingxue Fu; Jinlong Ru; Chao Huang; Jiangfeng Du; Chunli Zheng; Xuetong Chen; Pidong Li; Aiping Lu; Ling Yang; Yonghua Wang
Journal:  BMC Syst Biol       Date:  2014-12-24

4.  Overcoming Barriers to Development of Novel Therapies for Cardiovascular Disease: Insights From the Oncology Drug Development Experience.

Authors:  Aarif Y Khakoo; Nicole R Yurgin; Paul R Eisenberg; Gregg C Fonarow
Journal:  JACC Basic Transl Sci       Date:  2019-04-29

5.  Excessive leukotriene B4 in nucleus tractus solitarii is prohypertensive in spontaneously hypertensive rats.

Authors:  Hidefumi Waki; Emma B Hendy; Charles C T Hindmarch; Sabine Gouraud; Marie Toward; Sergey Kasparov; David Murphy; Julian F R Paton
Journal:  Hypertension       Date:  2012-11-19       Impact factor: 10.190

Review 6.  Neurogenic hypertension and elevated vertebrobasilar arterial resistance: is there a causative link?

Authors:  Matthew J Cates; C John Dickinson; Emma C J Hart; Julian F R Paton
Journal:  Curr Hypertens Rep       Date:  2012-06       Impact factor: 5.369
  6 in total

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