| Literature DB >> 21029967 |
Abstract
The ability of Toll-like receptors (TLRs) to activate innate immunity depends on their transport to pathogen-containing organelles. In this issue of Immunity, Husebye et al. (2010) report that delivery of TLR4 to phagosomes occurs via a recycling endosome intermediate, which is controlled by the GTPase Rab11a.Entities:
Year: 2010 PMID: 21029967 DOI: 10.1016/j.immuni.2010.10.003
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745