Literature DB >> 21029857

Ephecting excitatory synapse development.

Matthew B Dalva1.   

Abstract

Alterations in synapse number and morphology are associated with devastating psychiatric and neurologic disorders. In this issue of Cell, Margolis et al. (2010) show that the RhoA-guanine exchange factor (GEF) Ephexin5 limits the numbers of excitatory synapses that neurons receive, thus identifying a new mechanism controlling synaptogenesis.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 21029857      PMCID： PMC2976528          DOI： 10.1016/j.cell.2010.10.017

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin.

Authors:  S M Shamah; M Z Lin; J L Goldberg; S Estrach; M Sahin; L Hu; M Bazalakova; R L Neve; G Corfas; A Debant; M E Greenberg
Journal:  Cell       Date:  2001-04-20       Impact factor: 41.582

Review 2.  Cell adhesion molecules: signalling functions at the synapse.

Authors:  Matthew B Dalva; Andrew C McClelland; Matthew S Kayser
Journal:  Nat Rev Neurosci       Date:  2007-02-14       Impact factor: 34.870

3.  Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse.

Authors:  Mustafa Sahin; Paul L Greer; Michael Z Lin; Heather Poucher; Johann Eberhart; Susanne Schmidt; Tracy M Wright; Steven M Shamah; Sinead O'connell; Christopher W Cowan; Linda Hu; Jeffrey L Goldberg; Anne Debant; Gabriel Corfas; Catherine E Krull; Michael E Greenberg
Journal:  Neuron       Date:  2005-04-21       Impact factor: 17.173

4.  Ephexin1 is required for structural maturation and neurotransmission at the neuromuscular junction.

Authors:  Lei Shi; Busma Butt; Fanny C F Ip; Ying Dai; Liwen Jiang; Wing-Ho Yung; Michael E Greenberg; Amy K Y Fu; Nancy Y Ip
Journal:  Neuron       Date:  2010-01-28       Impact factor: 17.173

5.  RSY-1 is a local inhibitor of presynaptic assembly in C. elegans.

Authors:  Maulik R Patel; Kang Shen
Journal:  Science       Date:  2009-03-13       Impact factor: 47.728

6.  EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells.

Authors:  Hisakazu Ogita; Satoshi Kunimoto; Yuji Kamioka; Hirofumi Sawa; Michitaka Masuda; Naoki Mochizuki
Journal:  Circ Res       Date:  2003-05-29       Impact factor: 17.367

7.  Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.

Authors:  Steven W Flavell; Christopher W Cowan; Tae-Kyung Kim; Paul L Greer; Yingxi Lin; Suzanne Paradis; Eric C Griffith; Linda S Hu; Chinfei Chen; Michael E Greenberg
Journal:  Science       Date:  2006-02-17       Impact factor: 47.728

Review 8.  Angelman syndrome: current understanding and research prospects.

Authors:  Bernard Dan
Journal:  Epilepsia       Date:  2009-11       Impact factor: 5.864

9.  EphB receptors couple dendritic filopodia motility to synapse formation.

Authors:  Matthew S Kayser; Mark J Nolt; Matthew B Dalva
Journal:  Neuron       Date:  2008-07-10       Impact factor: 17.173
  9 in total
  2 in total

1.  The role of glutamate in the morphological and physiological development of dendritic spines.

Authors:  Hayley A Mattison; Dina Popovkina; Joseph P Y Kao; Scott M Thompson
Journal:  Eur J Neurosci       Date:  2014-03-24       Impact factor: 3.386

Review 2.  Emerging Roles of Ephexins in Physiology and Disease.

Authors:  Kwanhyeong Kim; Sang-Ah Lee; Daeho Park
Journal:  Cells       Date:  2019-01-24       Impact factor: 6.600
  2 in total

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