Literature DB >> 2100605

Inclusion complexation of doxorubicin and daunorubicin with cyclodextrins.

O Bekers1, J H Beijnen, M Otagiri, A Bult, W J Underberg.   

Abstract

The interaction of alpha-, beta- and gamma-cyclodextrins with the anthracycline antibiotics doxorubicin and daunorubicin was investigated by LC, circular dichroism (CD) and absorption spectroscopy. All studies were performed in aqueous media at different temperatures and pH values. The anthracyclines complex only with gamma-cyclodextrin. Lineweaver-Burk and Scott's plots were used to calculate the stability constants of the anthracycline-gamma-cyclodextrin inclusion complexes.

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Year:  1990        PMID： 2100605     DOI： 10.1016/0731-7085(90)80100-4

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN： 0731-7085            Impact factor:   3.935


  5 in total

1.  Development of self-forming doxorubicin-loaded polymeric depots as an injectable drug delivery system for liver cancer chemotherapy.

Authors:  Pinunta Nittayacharn; Norased Nasongkla
Journal:  J Mater Sci Mater Med       Date:  2017-05-22       Impact factor: 3.896

2.  Multifunctional drug nanocarriers formed by cRGD-conjugated βCD-PAMAM-PEG for targeted cancer therapy.

Authors:  Manju Saraswathy; Gavin T Knight; Srikanth Pilla; Randolph S Ashton; Shaoqin Gong
Journal:  Colloids Surf B Biointerfaces       Date:  2015-01-03       Impact factor: 5.268

3.  Preparation and evaluation of cyclodextrin polypseudorotaxane with PEGylated liposome as a sustained release drug carrier.

Authors:  Kayoko Hayashida; Taishi Higashi; Daichi Kono; Keiichi Motoyama; Koki Wada; Hidetoshi Arima
Journal:  Beilstein J Org Chem       Date:  2014-11-25       Impact factor: 2.883

4.  A biocompatible poly(amidoamine) (PAMAM) dendrimer octa-substituted with α-cyclodextrin towards the controlled release of doxorubicin hydrochloride from its ferrocenyl prodrug.

Authors:  Artur Kasprzak; Bartłomiej Dabrowski; Agnieszka Zuchowska
Journal:  RSC Adv       Date:  2020-06-19       Impact factor: 4.036

5.  Controlled Drug Release and Cytotoxicity Studies of Beta-Lapachone and Doxorubicin Loaded into Cyclodextrins Attached to a Polyethyleneimine Matrix.

Authors:  Agata Kowalczyk; Artur Kasprzak; Magdalena Poplawska; Monika Ruzycka; Ireneusz P Grudzinski; Anna M Nowicka
Journal:  Int J Mol Sci       Date:  2020-08-14       Impact factor: 6.208
  5 in total

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