| Literature DB >> 2100206 |
M S Suleiman1, N M Najib, M A Hassan, M E Abdel-Hamid.
Abstract
A new salt of ibuprofen was prepared by reaction with t-butylamine; its formation was confirmed by IR and 1H-NMR spectroscopy. The salt was characterized by thermoanalytical, X-ray powder diffraction and solubility studies. The salt was found to be 1.5 times more soluble in water than was ibuprofen, with an enthalpy of solution of -8.84 kcal mol-1.Entities:
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Year: 1990 PMID： 2100206 DOI： 10.1016/0731-7085(90)80045-q
Source DB: PubMed Journal: J Pharm Biomed Anal ISSN： 0731-7085 Impact factor: 3.935