Literature DB >> 20981216

Efficacy and long-term outcome of endoscopic treatment of sporadic nonampullary duodenal adenoma.

Hyung-Keun Kim1, Woo Chul Chung, Bo-In Lee, Young-Seok Cho.   

Abstract

BACKGROUND/AIMS: Endoscopic resection has proven to be a safe and effective alternative to surgery for duodenal adenomas. However, few data are available on the adequacy of resection and long-term outcomes. This study evaluated the efficacy and longterm endoscopic findings in a cohort of Korean patients who underwent endoscopic mucosal resection (EMR) of sporadic duodenal adenomas.
METHODS: Seventeen patients with nonampullary duodenal adenomas without familial polyposis syndrome and who were treated by EMR between January 2001 and December 2007 were evaluated retrospectively. Their management, follow-up, and outcomes were reviewed.
RESULTS: In total, seventeen lesions were removed from EMR in 17 patients (mean age, 59.3 years; 6 women, 11 men). The mean size of the tumors was 15.1 mm (median, 13 mm, range, 8-27 mm). Of these 17 adenomas, 16 adenomas were tubulous and 1 was tubulovillous. The EMR was performed successfully in all 17 patients in a single session. After a median follow-up period of 29 months (range, 13-72 months), all patients remained in remission. One patient had bleeding at the site of the EMR. There were no perforations after the EMR.
CONCLUSIONS: EMR for sporadic duodenal adenomas seemed to be a safe and effective treatment modality.

Entities:  

Keywords:  Adenoma; Duodenal neoplasm; Endoscopic mucosal resection; Treatment efficacy

Year:  2010        PMID: 20981216      PMCID: PMC2956351          DOI: 10.5009/gnl.2010.4.3.373

Source DB:  PubMed          Journal:  Gut Liver        ISSN: 1976-2283            Impact factor:   4.519


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