Literature DB >> 20980932

Altered gentamicin serum concentrations in obese pediatric patients.

Jamie J Choi1, Brady S Moffett, Erin J McDade, Debra L Palazzi.   

Abstract

We performed a retrospective case-cohort study of 50 obese pediatric patients aged 2 to 18 years who received scheduled gentamicin therapy, with serum peak and trough concentrations measured. Obese pediatric patients had significantly higher gentamicin serum peak and trough concentrations despite receiving significantly lower mg/kg of actual body weight doses of gentamicin.

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Year:  2011        PMID： 20980932     DOI： 10.1097/INF.0b013e3181ff023e

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  14 in total

1.  Medication Dosage in Overweight and Obese Children.

Authors:  Kelly L Matson; Evan R Horton; Amanda C Capino
Journal:  J Pediatr Pharmacol Ther       Date:  2017 Jan-Feb

2.  Comparison of Clinical Outcomes and Medication Use of Obese Versus Nonobese Children Admitted to the Pediatric Intensive Care Unit.

Authors:  Katy Stephens; Philip Barker; Erica Bergeron; Jamie L Miller; Tracy M Hagemann; Teresa V Lewis; Stephen Neely; Peter N Johnson
Journal:  Hosp Pharm       Date:  2019-12-19

3.  Implementation of a Pharmacist-Driven Vancomycin and Aminoglycoside Dosing Service in a Pediatric Hospital.

Authors:  Sara W Hovey; Jessica L Jacobson; Kristen M Welsh; Betty N Vu
Journal:  J Pediatr Pharmacol Ther       Date:  2022-05-09

4.  Protective effect of curcumin against experimentally induced aflatoxicosis on the renal cortex of adult male albino rats: a histological and immunohisochemical study.

Authors:  Abeer M El-Mahalaway
Journal:  Int J Clin Exp Pathol       Date:  2015-06-01

5.  Prescribing Patterns of Continuous Infusions in Nonobese versus Obese Children Admitted to the Pediatric Intensive Care Unit.

Authors:  Peter N Johnson; Katy Stephens; Philip Barker; Erica Bergeron; Sin Yin Lim; Tracy M Hagemann; Teresa V Lewis; Stephen Neely; Jamie L Miller
Journal:  J Pediatr Intensive Care       Date:  2019-06-21

6.  Method used to establish a large animal model of drug-induced acute kidney injury.

Authors:  Si-Yang Wang; Chao-Yang Zhang; Guang-Yan Cai; Xiang-Mei Chen
Journal:  Exp Biol Med (Maywood)       Date:  2021-01-19

Review 7.  Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic Review.

Authors:  Margreet W Harskamp-van Ginkel; Kevin D Hill; Kristian C Becker; Kristian Becker; Daniela Testoni; Michael Cohen-Wolkowiez; Daniel Gonzalez; Jeffrey S Barrett; Daniel K Benjamin; David A Siegel; Patricia Banks; Kevin M Watt
Journal:  JAMA Pediatr       Date:  2015-07       Impact factor: 26.796

8.  Pharmacokinetics of Clindamycin in Obese and Nonobese Children.

Authors:  Michael J Smith; Daniel Gonzalez; Jennifer L Goldman; Ram Yogev; Janice E Sullivan; Michael D Reed; Ravinder Anand; Karen Martz; Katherine Berezny; Daniel K Benjamin; P Brian Smith; Michael Cohen-Wolkowiez; Kevin Watt
Journal:  Antimicrob Agents Chemother       Date:  2017-03-24       Impact factor: 5.938

9.  Pharmacokinetics of Antimicrobials in Obese Children.

Authors:  Mr Sampson; M Cohen-Wolkowiez; Dk Benjamin; Ev Capparelli; Km Watt
Journal:  GaBI J       Date:  2013

10.  Protective Effects of Houttuynia cordata Thunb. on Gentamicin-induced Oxidative Stress and Nephrotoxicity in Rats.

Authors:  Changgeun Kang; Hyungkyoung Lee; Do-Yun Hah; Jung Ho Heo; Chung Hui Kim; Euikyung Kim; Jong Shu Kim
Journal:  Toxicol Res       Date:  2013-03
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