Literature DB >> 20980722

Systemic and cellular reflections on ageing and the circadian oscillator: a mini-review.

Steven A Brown1, Lucia Pagani, Christian Cajochen, Anne Eckert.   

Abstract

From circulation to digestion to excretion, a circadian clock synchronizes most aspects of mammalian physiology with the solar day. During normal ageing, this daily coordination gradually erodes, and during pathological ageing such erosion is exacerbated. Recent experiments suggest that therapies aimed at sustaining circadian function increase quality of life in elderly patients. Hence, a better understanding of the interactions between the circadian clock and ageing - at both cellular and systemic levels - could lead to direct benefits for aged individuals.
Copyright © 2010 S. Karger AG, Basel.

Entities:  

Mesh：

Year:  2010        PMID： 20980722     DOI： 10.1159/000320673

Source DB:  PubMed          Journal:  Gerontology        ISSN： 0304-324X            Impact factor:   5.140


  17 in total

1.  Human skin keratinocytes, melanocytes, and fibroblasts contain distinct circadian clock machineries.

Authors:  Cristina Sandu; Marc Dumas; André Malan; Diariétou Sambakhe; Clarisse Marteau; Carine Nizard; Sylvianne Schnebert; Eric Perrier; Etienne Challet; Paul Pévet; Marie-Paule Felder-Schmittbuhl
Journal:  Cell Mol Life Sci       Date:  2012-05-25       Impact factor: 9.261

2.  A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude.

Authors:  Yagmur Umay Doruk; Darya Yarparvar; Yasemin Kubra Akyel; Seref Gul; Ali Cihan Taskin; Fatma Yilmaz; Ibrahim Baris; Nuri Ozturk; Metin Türkay; Narin Ozturk; Alper Okyar; Ibrahim Halil Kavakli
Journal:  J Biol Chem       Date:  2020-02-04       Impact factor: 5.157

Review 3.  The brain-joint axis in osteoarthritis: nerves, circadian clocks and beyond.

Authors:  Francis Berenbaum; Qing-Jun Meng
Journal:  Nat Rev Rheumatol       Date:  2016-06-16       Impact factor: 20.543

Review 4.  Sleep behavior across the lifespan: How a model can expand our current understanding.

Authors:  Stephanie J Crowley
Journal:  Sleep Med Rev       Date:  2015-12-17       Impact factor: 11.609

Review 5.  Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems.

Authors:  Zheng Chen; Seung-Hee Yoo; Joseph S Takahashi
Journal:  Annu Rev Pharmacol Toxicol       Date:  2017-10-02       Impact factor: 13.820

6.  Time-place learning over a lifetime: absence of memory loss in trained old mice.

Authors:  Cornelis K Mulder; Gerlof A R Reckman; Menno P Gerkema; Eddy A Van der Zee
Journal:  Learn Mem       Date:  2015-04-22       Impact factor: 2.460

Review 7.  Manipulating the circadian and sleep cycles to protect against metabolic disease.

Authors:  Kazunari Nohara; Seung-Hee Yoo; Zheng Jake Chen
Journal:  Front Endocrinol (Lausanne)       Date:  2015-03-23       Impact factor: 5.555

8.  The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis.

Authors:  Nicole Gossan; Leo Zeef; James Hensman; Alun Hughes; John F Bateman; Lynn Rowley; Christopher B Little; Hugh D Piggins; Magnus Rattray; Raymond P Boot-Handford; Qing-Jun Meng
Journal:  Arthritis Rheum       Date:  2013-09

9.  Gremlin-2 is a BMP antagonist that is regulated by the circadian clock.

Authors:  Ching-Yan Chloé Yeung; Nicole Gossan; Yinhui Lu; Alun Hughes; James J Hensman; Monika L Bayer; Michael Kjær; Karl E Kadler; Qing-Jun Meng
Journal:  Sci Rep       Date:  2014-06-05       Impact factor: 4.379

Review 10.  Ageing and osteoarthritis: a circadian rhythm connection.

Authors:  Nicole Gossan; Ray Boot-Handford; Qing-Jun Meng
Journal:  Biogerontology       Date:  2014-07-31       Impact factor: 4.277
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