Literature DB >> 20980490

Rice intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study.

Akiko Nanri1, Tetsuya Mizoue, Mitsuhiko Noda, Yoshihiko Takahashi, Masayuki Kato, Manami Inoue, Shoichiro Tsugane.   

Abstract

BACKGROUND: Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, which is a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear.
OBJECTIVE: We prospectively investigated the association between white rice intake and risk of type 2 diabetes.
DESIGN: Participants were 25,666 men and 33,622 women aged 45-75 y who participated in the second survey of the Japan Public Health Center-based Prospective Study and who had no prior history of diabetes. We ascertained food intake by using a validated 147-item food-frequency questionnaire. Odds ratios of self-reported, physician-diagnosed type 2 diabetes over 5 y were estimated by using logistic regressions.
RESULTS: A total of 1103 new cases of type 2 diabetes were self-reported. There was a significant association between rice intake and an increased risk of type 2 diabetes in women; the multivariate-adjusted odds ratio for the highest compared with lowest quartiles of rice intake was 1.65 (95% CI: 1.06, 2.57; P for trend = 0.005). In men, the association was unclear, although there was a suggestion of a positive association in persons who were not engaged in strenuous physical activity (P for trend = 0.08).
CONCLUSIONS: Elevated intake of white rice is associated with an increased risk of type 2 diabetes in Japanese women. The finding that is suggestive of a positive association of rice intake in physically inactive men deserves further investigation.

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Year:  2010        PMID: 20980490     DOI: 10.3945/ajcn.2010.29512

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


  66 in total

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