| Literature DB >> 20980167 |
Rahmi Oklu1, Thomas G Walker, Stephan Wicky, Robin Hesketh.
Abstract
Angiogenesis is a complex process critical for embryonic development and for survival. It is also a critical player in many pathologic processes, most notably in neoplasia. The cell signaling pathways involved in angiogenesis have become key targets for drug design, with more than 2,500 clinical trials currently under way. This review summarizes the essential features of angiogenesis and discusses therapeutic strategies that have been applied to specific diseases known to be associated with perturbation of normal angiogenic control.Entities:
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Year: 2010 PMID: 20980167 DOI: 10.1016/j.jvir.2010.08.009
Source DB: PubMed Journal: J Vasc Interv Radiol ISSN: 1051-0443 Impact factor: 3.464