Literature DB >> 20980167

Angiogenesis and current antiangiogenic strategies for the treatment of cancer.

Rahmi Oklu1, Thomas G Walker, Stephan Wicky, Robin Hesketh.   

Abstract

Angiogenesis is a complex process critical for embryonic development and for survival. It is also a critical player in many pathologic processes, most notably in neoplasia. The cell signaling pathways involved in angiogenesis have become key targets for drug design, with more than 2,500 clinical trials currently under way. This review summarizes the essential features of angiogenesis and discusses therapeutic strategies that have been applied to specific diseases known to be associated with perturbation of normal angiogenic control.
Copyright © 2010 SIR. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20980167     DOI: 10.1016/j.jvir.2010.08.009

Source DB:  PubMed          Journal:  J Vasc Interv Radiol        ISSN: 1051-0443            Impact factor:   3.464


  27 in total

1.  Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression.

Authors:  Anne-Laure Pin; François Houle; Patrick Fournier; Maëva Guillonneau; Éric R Paquet; Martin J Simard; Isabelle Royal; Jacques Huot
Journal:  J Biol Chem       Date:  2012-07-06       Impact factor: 5.157

2.  Regulation of Tumor Angiogenesis and Choroidal Neovascularization by Endogenous Angioinhibitors.

Authors:  Venugopal Gunda; Yakkanti A Sudhakar
Journal:  J Cancer Sci Ther       Date:  2013-07-04

Review 3.  Targeting angiogenesis and the tumor microenvironment.

Authors:  Jennifer Samples; Monte Willis; Nancy Klauber-Demore
Journal:  Surg Oncol Clin N Am       Date:  2013-07-26       Impact factor: 3.495

4.  VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis.

Authors:  Chandran S Abhinand; Rajesh Raju; Sasikumar J Soumya; Prabha S Arya; Perumana R Sudhakaran
Journal:  J Cell Commun Signal       Date:  2016-09-12       Impact factor: 5.782

5.  Are epsins a therapeutic target for tumor angiogenesis?

Authors:  Nancy Klauber-Demore
Journal:  J Clin Invest       Date:  2012-11-26       Impact factor: 14.808

6.  Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells.

Authors:  Baoshan Cao; Jun Jia; Liwen Ma; Lijun Di; Guohong Song; Yanhua Yuan; Bo Ma; Yulin Zhu; Jing Yu; Xiaoli Wang; Xinna Zhou; H Kim Lyerly; Jun Ren
Journal:  Clin Transl Oncol       Date:  2012-07-21       Impact factor: 3.405

7.  Targeting angiogenesis for controlling neuroblastoma.

Authors:  Subhasree Roy Choudhury; Surajit Karmakar; Naren L Banik; Swapan K Ray
Journal:  J Oncol       Date:  2011-08-25       Impact factor: 4.375

8.  In vivo time-course imaging of tumor angiogenesis in colorectal liver metastases in the same living mice using two-photon laser scanning microscopy.

Authors:  Koji Tanaka; Yuhki Morimoto; Yuji Toiyama; Kohei Matsushita; Mikio Kawamura; Yuhki Koike; Yoshinaga Okugawa; Yasuhiro Inoue; Keiichi Uchida; Toshimitsu Araki; Akira Mizoguchi; Masato Kusunoki
Journal:  J Oncol       Date:  2011-11-03       Impact factor: 4.375

9.  Prognostic Significance of Microvessel Density Determining by Endoglin in Stage II Rectal Carcinoma: A Retrospective Analysis.

Authors:  Zeljko Martinovic; Drazen Kovac; Mia Martinovic
Journal:  Gastroenterol Res Pract       Date:  2015-05-21       Impact factor: 2.260

Review 10.  Venous endothelial injury in central nervous system diseases.

Authors:  Jonathan S Alexander; Leonard Prouty; Ikuo Tsunoda; Chaitanya Vijay Ganta; Alireza Minagar
Journal:  BMC Med       Date:  2013-10-11       Impact factor: 8.775

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