Jun-ping Wu1, Zhen-ya Song, Yi Xu, Yi-min Zhang, Rong-hai Shen. 1. Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China. wjp86207@163.com
Abstract
OBJECTIVE: To investigate the sleep features in the patients with irritable bowel syndrome (IBS) and compare the sleep quality between those IBS patients who were with and without anxiety and depression. METHODS: Pittsburgh sleep quality index questionnaire (PSQI), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were measured in the 145 IBS patients and 59 regular physical examination volunteers. IBS patients were also divided into two subgroups--patients with or without anxiety and depression based on cutoff scores of SAS and SDS. Comparisons of sleep quality were made between subgroups, and between IBS patients and volunteer controls. RESULTS: Compared with the controls, the SAS raw score, SDS raw score and SAS positive incidence in IBS patients were shown statistically significant differences (P<0.05), while the SDS positive incidence had no statistically significant difference (P>0.05). PSQI total scores were significantly higher in the IBS patients without anxiety and depression (P<0.05), 3 domains (sleep quality, sleep disturbances and daytime function disorder) were also found statistically significant differences (P<0.05), compared with the controls. The IBS patients with anxiety and depression were statistically significantly different from the controls (P<0.05) in 6 domains (sleep quality, sleep latency, sleep efficiency, sleep disturbances, sleep time and daytime function disorder) and significantly higher PSQI total scores (P<0.05). Statistically significant differences (P<0.05) were also found in all 7 domains and with higher PSQI total scores in IBS patients with anxiety and depression, compared with IBS patients without anxiety and depression. CONCLUSIONS: IBS patients were more likely to have sleep abnormality, mainly in sleep quality, sleep disturbances and daytime function disorder and PSQI total scores. The abnormalities of these factors were independent of emotional disorder. However, emotional disorder worsened the sleep disorder in IBS patients.
OBJECTIVE: To investigate the sleep features in the patients with irritable bowel syndrome (IBS) and compare the sleep quality between those IBSpatients who were with and without anxiety and depression. METHODS: Pittsburgh sleep quality index questionnaire (PSQI), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were measured in the 145 IBSpatients and 59 regular physical examination volunteers. IBSpatients were also divided into two subgroups--patients with or without anxiety and depression based on cutoff scores of SAS and SDS. Comparisons of sleep quality were made between subgroups, and between IBSpatients and volunteer controls. RESULTS: Compared with the controls, the SAS raw score, SDS raw score and SAS positive incidence in IBSpatients were shown statistically significant differences (P<0.05), while the SDS positive incidence had no statistically significant difference (P>0.05). PSQI total scores were significantly higher in the IBSpatients without anxiety and depression (P<0.05), 3 domains (sleep quality, sleep disturbances and daytime function disorder) were also found statistically significant differences (P<0.05), compared with the controls. The IBSpatients with anxiety and depression were statistically significantly different from the controls (P<0.05) in 6 domains (sleep quality, sleep latency, sleep efficiency, sleep disturbances, sleep time and daytime function disorder) and significantly higher PSQI total scores (P<0.05). Statistically significant differences (P<0.05) were also found in all 7 domains and with higher PSQI total scores in IBSpatients with anxiety and depression, compared with IBSpatients without anxiety and depression. CONCLUSIONS:IBSpatients were more likely to have sleep abnormality, mainly in sleep quality, sleep disturbances and daytime function disorder and PSQI total scores. The abnormalities of these factors were independent of emotional disorder. However, emotional disorder worsened the sleep disorder in IBSpatients.