Literature DB >> 20978572

Perigraft hemorrhage after abdominal aortic aneurysm repair in a heart transplant patient.

Mehmet H Akay1, Christoph S Nabzdyk, Igor D Gregoric, O H Frazier.   

Abstract

Spontaneous perigraft hemorrhage can occur years after a successful aortic aneurysm repair. Such hemorrhage can result, in part, from inadequate graft healing. Herein, we describe the case of a heart transplant recipient who underwent an abdominal aortic aneurysm repair that was complicated by an acute perigraft leak 6 weeks later. Apparently, suppression of the patient's immune system impaired proper healing of the graft-aortic anastomosis site. In patients who have a compromised immune system, an additional 4-0 polypropylene pledgeted suture line should be placed for reinforcement during abdominal aortic aneurysm repair. Postoperatively, patients who are given immunosuppressive therapy should undergo careful, long-term monitoring.

Entities:  

Keywords:  Aortic aneurysm, abdominal/epidemiology/surgery; heart transplantation; immunosuppressive agents/adverse effects/therapeutic use; postoperative complications/prevention & control/surgery; risk factors; tomography, X-ray computed; wound healing/drug effects

Mesh:

Substances:

Year:  2010        PMID: 20978572      PMCID: PMC2953217     

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  12 in total

1.  Spontaneous perigraft hematoma suggesting transgraft hemorrhage seven years after thoracic aortic replacement with a Dacron graft.

Authors:  Norihiko Shiiya; Takashi Kunihara; Kenji Matsuzaki; Takashi Sugiki
Journal:  Eur J Cardiothorac Surg       Date:  2006-07-07       Impact factor: 4.191

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Journal:  Thorac Cardiovasc Surg       Date:  1986-02       Impact factor: 1.827

3.  In vitro evidence for a direct antifibrotic role of the immunosuppressive drug mycophenolate mofetil.

Authors:  Nina Roos; Nicolas Poulalhon; Dominique Farge; Isabelle Madelaine; Alain Mauviel; Franck Verrecchia
Journal:  J Pharmacol Exp Ther       Date:  2007-02-01       Impact factor: 4.030

4.  Prevention of neointimal proliferation by immunosuppression in synthetic vascular grafts.

Authors:  B H Walpoth; M Pavlicek; B Celik; B Nicolaus; T Schaffner; U Althaus; O M Hess; T Carrel; R E Morris
Journal:  Eur J Cardiothorac Surg       Date:  2001-04       Impact factor: 4.191

5.  Mycophenolate mofetil impairs the integrity of colonic anastomosis.

Authors:  Nicholas Sikas; George Imvrios; Dimitrios Takoudas; Dimitrios Gakis; Vasilios Papanikolaou
Journal:  J Surg Res       Date:  2006-03-29       Impact factor: 2.192

6.  Abdominal aortic aneurysms after heart transplantation.

Authors:  Pascal J M J Vantrimpont; Bastiaan M van Dalen; Iza C van Riemsdijk-van Overbeeke; Alex P W M Maat; Aggie H M M Balk
Journal:  J Heart Lung Transplant       Date:  2004-02       Impact factor: 10.247

7.  Steroids and immunosuppression. Effect on anastomotic intimal hyperplasia in femoral arterial dacron bypass grafts.

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Journal:  Arch Surg       Date:  1979-03

8.  Cyclosporine A delays wound healing and apoptosis and suppresses activin beta-A expression in rats.

Authors:  J B Petri; S Schurk; S Gebauer; U F Haustein
Journal:  Eur J Dermatol       Date:  1998-03       Impact factor: 3.328

9.  Significance of T-lymphocytes in wound healing.

Authors:  J M Peterson; A Barbul; R J Breslin; H L Wasserkrug; G Efron
Journal:  Surgery       Date:  1987-08       Impact factor: 3.982

10.  Efficacy of corticosteroids in suppression of intimal hyperplasia.

Authors:  A Chervu; W S Moore; W J Quiñones-Baldrich; T Henderson
Journal:  J Vasc Surg       Date:  1989-08       Impact factor: 4.268

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