Literature DB >> 20976623

Long-term recurrence rates following dilation of symptomatic Schatzki rings.

Michaela Müller1, Ines Gockel, Jochem König, Kathrin Kuhr, Volker F Eckardt.   

Abstract

BACKGROUND AND AIMS: This study investigated the long-term clinical course of patients with Schatzki rings, who were treated by single bougie dilation. Furthermore, it analyzed possible predictors for the time of recurrence. PATIENTS AND METHODS: A total of 133 patients (100 males, 33 females) with a mean age of 57 ± 14.6 years who were treated by single dilation with the use of Maloney bougies without the aid of fluoroscopy were prospectively registered and followed-up for a mean duration of 58.3 months (range 12-240 months). Duration of remission was evaluated by Kaplan-Meier estimates with regard to recurrence. Log-rank test was performed to analyze possible predictors for the time to second dilation (recurrence).
RESULTS: No complications occurred and all patients were symptom-free at the first follow-up examination 4 weeks after dilation. However, later on, 73 patients required a second dilation. The estimate remission rates were 63.8% (95% CI: 55.6-72.0%) after 2 years, 44.3% (95% CI: 35.4-53.4%) after 5 years, and 39.9% (95% CI: 30.5-49.3%) after 10 years. Neither the initial morphological findings, nor age or gender determined the need for repeated dilation. Only patients treated with a large bougie diameter (≥52 F) seemed to have a tendency for a longer time until symptomatic recurrence.
CONCLUSIONS: Single dilation of symptomatic Schatzki rings is a safe and effective therapy. However, more than half of the patients will need a second treatment. Recurrences are unrelated to initial morphological findings, age, or gender. Only the treatment with a large bougie diameter (≥52 F) showed a tendency for a longer time of remission.

Entities:  

Mesh:

Year:  2010        PMID: 20976623     DOI: 10.1007/s10620-010-1427-7

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  29 in total

1.  THE LOWER ESOPHAGEAL RING. LONG TERM FOLLOW-UP OF SYMPTOMATIC AND ASYMPTOMATIC RINGS.

Authors:  R SCHATZKI
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1963-10

2.  THE ANATOMIC BASIS FOR THE LOWER ESOPHAGEAL CONTRACTION RING. PLICATION THEORY AND ITS APPLICATIONS.

Authors:  O A STIENNON
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1963-10

3.  Dysphagia due to a diaphragm-like localized narrowing in the lower esophagus (lower esophageal ring).

Authors:  R SCHATZKI; J E GARY
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1953-12

Review 4.  Esophageal rings, webs, and diverticula.

Authors:  R W Tobin
Journal:  J Clin Gastroenterol       Date:  1998-12       Impact factor: 3.062

5.  Late results in patients with Schatzki ring treated by endoscopic electrosurgical incision of the ring.

Authors:  M Guelrud; L Villasmil; R Mendez
Journal:  Gastrointest Endosc       Date:  1987-04       Impact factor: 9.427

6.  The lower esophageal ring and esophageal reflux.

Authors:  B F Scharschmidt; H D Watts
Journal:  Am J Gastroenterol       Date:  1978-05       Impact factor: 10.864

7.  Effectiveness of single dilation with Maloney dilator versus endoscopic rupture of Schatzki's ring using biopsy forceps.

Authors:  P Chotiprasidhi; A Minocha
Journal:  Dig Dis Sci       Date:  2000-02       Impact factor: 3.199

8.  Gastroesophageal reflux as a pathogenic factor in the development of symptomatic lower esophageal rings.

Authors:  J B Marshall; J M Kretschmar; A A Diaz-Arias
Journal:  Arch Intern Med       Date:  1990-08

9.  Lower esophageal ring: experiences in treatment of 88 patients.

Authors:  C E Eastridge; J W Pate; J A Mann
Journal:  Ann Thorac Surg       Date:  1984-02       Impact factor: 4.330

10.  Correlation of lower esophageal mucosal ring and 24-h pH monitoring of the esophagus.

Authors:  D J Ott; M S Ledbetter; M Y Chen; J A Koufman; D W Gelfand
Journal:  Am J Gastroenterol       Date:  1996-01       Impact factor: 10.864

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.