Literature DB >> 20975882

Complete response of hepatocellular carcinoma with sorafenib and Y radioembolization.

P K Chaudhury1, M Hassanain, J M Bouteaud, T Alcindor, C G Nudo, D Valenti, T Cabrera, P Kavan, I Feteih, P Metrakos.   

Abstract

Advanced hepatocellular carcinoma has a dismal prognosis, with a median overall survival of 7.9 months if untreated and of 10.7 months if treated with sorafenib. We present a case of advanced previously unresectable hepatocellular carcinoma in a 49-year-old man that achieved a pathologic complete response and was made amenable to surgery with sorafenib in combination with (90)Y radioembolization. The patient's survival was more than double the median for patients treated with sorafenib alone.

Entities:  

Keywords:  Cancer; gastrointestinal; oncology; surgery

Year:  2010        PMID： 20975882      PMCID： PMC2949375          DOI： 10.3747/co.v17i5.609

Source DB:  PubMed          Journal:  Curr Oncol        ISSN： 1198-0052            Impact factor:   3.677


  7 in total

Review 1.  Radiologic findings following Y90 radioembolization for primary liver malignancies.

Authors:  Saad M Ibrahim; Paul Nikolaidis; Frank H Miller; Robert J Lewandowski; Robert K Ryu; Kent T Sato; Sean Senthilnathan; Ahsun Riaz; Laura Kulik; Mary F Mulcahy; Reed A Omary; Riad Salem
Journal:  Abdom Imaging       Date:  2009 Sep-Oct

2.  Global cancer statistics, 2002.

Authors:  D Max Parkin; Freddie Bray; J Ferlay; Paola Pisani
Journal:  CA Cancer J Clin       Date:  2005 Mar-Apr       Impact factor: 508.702

Review 3.  Design of clinical trials of radiation combined with antiangiogenic therapy.

Authors:  Suresh Senan; Egbert F Smit
Journal:  Oncologist       Date:  2007-04

Review 4.  Hepatocellular carcinoma.

Authors:  Josep M Llovet; Andrew Burroughs; Jordi Bruix
Journal:  Lancet       Date:  2003-12-06       Impact factor: 79.321

Review 5.  Radioembolization for the treatment of unresectable hepatocellular carcinoma: a clinical review.

Authors:  Saad-M Ibrahim; Robert-J Lewandowski; Kent-T Sato; Vanessa-L Gates; Laura Kulik; Mary-F Mulcahy; Robert-K Ryu; Reed-A Omary; Riad Salem
Journal:  World J Gastroenterol       Date:  2008-03-21       Impact factor: 5.742

Review 6.  Novel advancements in the management of hepatocellular carcinoma in 2008.

Authors:  Josep M Llovet; Jordi Bruix
Journal:  J Hepatol       Date:  2008-02-12       Impact factor: 25.083

7.  Sorafenib in advanced hepatocellular carcinoma.

Authors:  Josep M Llovet; Sergio Ricci; Vincenzo Mazzaferro; Philip Hilgard; Edward Gane; Jean-Frédéric Blanc; Andre Cosme de Oliveira; Armando Santoro; Jean-Luc Raoul; Alejandro Forner; Myron Schwartz; Camillo Porta; Stefan Zeuzem; Luigi Bolondi; Tim F Greten; Peter R Galle; Jean-François Seitz; Ivan Borbath; Dieter Häussinger; Tom Giannaris; Minghua Shan; Marius Moscovici; Dimitris Voliotis; Jordi Bruix
Journal:  N Engl J Med       Date:  2008-07-24       Impact factor: 91.245
  7 in total
  7 in total

Review 1.  Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies.

Authors:  Yasunobu Matsuda; Takafumi Ichida; Manabu Fukumoto
Journal:  Med Mol Morphol       Date:  2011-09-16       Impact factor: 2.309

2.  Reproducible complete remission of advanced hepatocellular carcinoma with sorafenib in combination with clopidogrel.

Authors:  Jocelyn L Tan-Shalaby
Journal:  BMJ Case Rep       Date:  2014-09-01

3.  Combined sorafenib and yttrium-90 radioembolization for the treatment of advanced hepatocellular carcinoma.

Authors:  A Salman; E Simoneau; M Hassanain; P Chaudhury; L M Boucher; D Valenti; T Cabrera; C Nudo; P Metrakos
Journal:  Curr Oncol       Date:  2016-10-25       Impact factor: 3.677

Review 4.  The role of interventional radiology in the management of hepatocellular carcinoma.

Authors:  N Molla; N AlMenieir; E Simoneau; M Aljiffry; D Valenti; P Metrakos; L M Boucher; M Hassanain
Journal:  Curr Oncol       Date:  2014-06       Impact factor: 3.677

5.  (210)Po microsphere radiological design for tumor vascular disruption.

Authors:  J J Bevelacqua
Journal:  PeerJ       Date:  2015-08-04       Impact factor: 2.984

6.  Tumor vascular disruption using various radiation types.

Authors:  Jj Bevelacqua
Journal:  PeerJ       Date:  2014-04-01       Impact factor: 2.984

7.  An eight cytokine signature identified from peripheral blood serves as a fingerprint for hepatocellular cancer diagnosis.

Authors:  Jing Shen; Hua Wu; Ning Peng; Jie Cai
Journal:  Afr Health Sci       Date:  2018-06       Impact factor: 0.927
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.