Literature DB >> 20975846

Expected Power for the False Discovery Rate with Independence.

D H Glueck1, K E Muller, A Karimpour-Fard, L Hunter.   

Abstract

The Benjamini-Hochberg procedure is widely used in multiple comparisons. Previous power results for this procedure have been based on simulations. This article produces theoretical expressions for expected power. To derive them, we make assumptions about the number of hypotheses being tested, which null hypotheses are true, which are false, and the distributions of the test statistics under each null and alternative. We use these assumptions to derive bounds for multiple dimensional rejection regions. With these bounds and a permanent based representation of the joint density function of the largest p-values, we use the law of total probability to derive the distribution of the total number of rejections. We derive the joint distribution of the total number of rejections and the number of rejections when the null hypothesis is true. We give an analytic expression for the expected power for a false discovery rate procedure that assumes the hypotheses are independent.

Year:  2008        PMID: 20975846      PMCID: PMC2962418          DOI: 10.1080/03610920801893731

Source DB:  PubMed          Journal:  Commun Stat Theory Methods        ISSN: 0361-0926            Impact factor:   0.893


  3 in total

Review 1.  Multiple comparisons: philosophies and illustrations.

Authors:  D Curran-Everett
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2000-07       Impact factor: 3.619

2.  Controlling the rate of Type I error over a large set of statistical tests.

Authors:  H J Keselman; Robert Cribbie; Burt Holland
Journal:  Br J Math Stat Psychol       Date:  2002-05       Impact factor: 3.380

3.  Power and sample size for DNA microarray studies.

Authors:  Mei-Ling Ting Lee; G A Whitmore
Journal:  Stat Med       Date:  2002-12-15       Impact factor: 2.373

  3 in total
  3 in total

1.  Fast Computation by Block Permanents of Cumulative Distribution Functions of Order Statistics from Several Populations.

Authors:  D H Glueck; A Karimpour-Fard; J Mandel; L Hunter; K E Muller
Journal:  Commun Stat Theory Methods       Date:  2008-01-01       Impact factor: 0.893

2.  Exact calculations of average power for the Benjamini-Hochberg procedure.

Authors:  Deborah H Glueck; Jan Mandel; Anis Karimpour-Fard; Lawrence Hunter; Keith E Muller
Journal:  Int J Biostat       Date:  2008       Impact factor: 0.968

3.  Probabilities for separating sets of order statistics.

Authors:  D H Glueck; A Karimpour-Fard; J Mandel; K E Muller
Journal:  Statistics (Ber)       Date:  2010-04-01       Impact factor: 1.051

  3 in total

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