| Literature DB >> 20975842 |
Abstract
High-density lipoprotein (HDL) is proposed to inhibit atherosclerosis via a number of different pathways, including promotion of reverse cholesterol transport and inhibition of inflammation. However, studies in both mice and humans suggest that quantifying HDL-cholesterol (HDL-C) levels provide limited information regarding the cardioprotective effects of HDL. This article briefly reviews current thinking regarding the functional and cardioprotective effects of HDL and the role of the HDL proteome in these processes.Entities:
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Year: 2010 PMID: 20975842 PMCID: PMC2959168 DOI: 10.1016/j.jacl.2010.08.005
Source DB: PubMed Journal: J Clin Lipidol ISSN: 1876-4789 Impact factor: 4.766