Literature DB >> 20973175

[Chaperones in regulation and restoration of physiological functions].

Iu F Pastukhov, K A Khudik, I V Ekimova.   

Abstract

Protective effects of the HSP70 expression in heat stress, sleep deprivation, epilepsy, enhanced anxiety, psycho-emotional stress, physical loads, are described, and data on the HSP70 effects upon characteristics of sleep and somatic-visceral functions in homeothermic animals are cited. Prospects of using the HSP70 "inductors" are discussed as well as the HSP70 preparations use in therapy of large range of pathological conditions.

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Year:  2010        PMID： 20973175

Source DB:  PubMed          Journal:  Ross Fiziol Zh Im I M Sechenova        ISSN： 0869-8139


  3 in total

1.  Chaperone Hsp70 is involved in the molecular mechanisms of slow wave sleep regulation.

Authors:  Iu F Pastukhov; V V Simonova; M A Guzeev; D A Meshalkina; I V Guzhova; I V Ekimova
Journal:  Dokl Biochem Biophys       Date:  2015-05-05       Impact factor: 0.788

2.  Somnogenic effect of exogenous heat shock protein 70 kDa is mediated by GABA(A) receptors in the preoptic area of the hypothalamus.

Authors:  I V Ekimova
Journal:  Dokl Biol Sci       Date:  2013-05-08

3.  Exogenous protein HSP70 blocks neurodegeneration in the rat model of the clinical stage of Parkinson's disease.

Authors:  Yu F Pastukhov; D V Plaksina; K V Lapshina; I V Guzhova; I V Ekimova
Journal:  Dokl Biol Sci       Date:  2014-08-30
  3 in total

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