Literature DB >> 20972970

Intralesional corticosteroid injection and dilatation provides effective management of subglottic stenosis in Wegener's granulomatosis.

Nikolaus E Wolter1, Eng Hooi Ooi, Ian J Witterick.   

Abstract

OBJECTIVES/HYPOTHESIS: To describe our experience with the use of intralesional corticosteroid injection and dilatation (ILCD) in the management of subglottic stenosis (SGS). STUDY
DESIGN: Retrospective chart review.
METHODS: A retrospective chart review was performed of all patients with SGS requiring ILCD, from 2003 to 2008, at the Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Hospital, Toronto, Canada.
RESULTS: Twelve patients with SGS underwent 36 ILCD operations with a mean of three procedures per patient. We identified eight patients with Wegener's granulomatosis (WG) and four patients without WG. The eight WG patients received an average of 3.37 procedures, whereas non-WG patients required an average of 2.25 procedures. This maintained airway patency and symptom control for an average of 11.9 and 8.1 months, respectively. Only one complication was identified, and no long-term sequelae were found. No patients required new tracheotomies and one patient with a previous tracheotomy was successfully decannulated.
CONCLUSIONS: Our data supports the use of ILCD as a safe and effective treatment of SGS in both WG and non-WG patients.

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Year:  2010        PMID: 20972970     DOI: 10.1002/lary.21121

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  9 in total

1.  [Subglottic tracheal stenosis].

Authors:  N Karaiskaki; W J Mann
Journal:  HNO       Date:  2012-06       Impact factor: 1.284

2.  Update on the treatment of granulomatosis with polyangiitis (Wegener's).

Authors:  Carol A Langford
Journal:  Curr Treat Options Cardiovasc Med       Date:  2012-04

3.  Evaluation of smell and taste in patients with Wegener's granulomatosis.

Authors:  James A Fasunla; Walter Hundt; Jens Lutz; Frauke Förger; Klaus Thürmel; Silke Steinbach
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-07-12       Impact factor: 2.503

4.  Magnetic resonance imaging in patients with granulomatosis with polyangiitis (Wegener's) and subglottic stenosis.

Authors:  Thorsten Klink; Julia Holle; Martin Laudien; Frank Oliver Henes; Frank Moosig; Corinna Platzek; Gerhard Adam; Wolfgang-Ludwig Gross; Thorsten Alexander Bley
Journal:  MAGMA       Date:  2012-10-20       Impact factor: 2.310

5.  Clinical aspects of granulomatosis with polyangiitis affecting the head and neck.

Authors:  Andreas Knopf; Adam Chaker; Thomas Stark; Benedikt Hofauer; Tobias Lahmer; Klaus Thürmel; Murat Bas
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-03-09       Impact factor: 2.503

6.  Treatment for adult idiopathic and Wegener-associated subglottic stenosis.

Authors:  Haralampos Gouveris; Niki Karaiskaki; Dimitrios Koutsimpelas; Cheerasook Chongolwatana; Wolf Mann
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-11-07       Impact factor: 2.503

7.  Serial In-Office Intralesional Steroid Injections in Airway Stenosis.

Authors:  Caitlin Bertelsen; Hagit Shoffel-Havakuk; Karla O'Dell; Michael M Johns; Lindsay S Reder
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2018-03-01       Impact factor: 6.223

8.  Life-Threatening Subglottic Stenosis of Granulomatosis with Polyangiitis: A Case Report.

Authors:  Jin An; Jae-Won Song
Journal:  Medicina (Kaunas)       Date:  2021-04-27       Impact factor: 2.430

9.  Office-based corticosteroid injections as adjuvant therapy for subglottic stenosis.

Authors:  Debbie R Pan; David E Rosow
Journal:  Laryngoscope Investig Otolaryngol       Date:  2019-06-10
  9 in total

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