OBJECTIVE: To evaluate the feasibility and outcome of home-based rehabilitation of severely malnourished children. DESIGN: Prospective and observational. SETTING: Rehabilitation at home (16 weeks) following initial assessment or/and stabilization at hospital. PARTICIPANTS: Thirty-four severely malnourished (weight for length < 70% of WHO reference) children between the ages of 6 months to 5 years. INTERVENTION: Initial assessment of the patient was done in hospital. Those with complications or loss of appetite were admitted in hospital and managed as per WHO guidelines. After discharge, they were managed at home using home based diets. Those without complications and with preserved appetite were directly eligible for home-based rehabilitation. Follow up was done in hospital up to 16 weeks. Dietary intake, anthropometry and morbidities were recorded during follow-up. RESULTS: Of the enrolled 34 children, 19 children were admitted in hospital and 15 children were sent home after initial assessment in hospital. Five did not clear the initial stabilization phase (2 died, 3 left hospital). Finally 29 children qualified for home based rehabilitation out of which 26 completed 16 week follow-up. During the home based management phase, the reported mean (±SD) calorie intake increased from 100 (± 5) kcal/kg/d at entry point to 243 (± 13) kcal/kg/d at 16 weeks (P=0.000). Similarly, reported protein intake increased from 1.1 (± 0.3) g/kg/d to 4.8 (± 0.3) g/kg/d (P=0.000). During hospital stay (n=19), children had weight gain of 9.0 (±5.3) g/kg/d, while during home based follow up (n=29), weight gain was 3.2 (± 1.5) g/kg/d only. During home based rehabilitation, only 3 (11.5%) children had weight gain of more than 5 g/kg/d by the end of 16 weeks. Weight for height percent increased from an average (± SD) of 62.9% (± 6.0%) to 80.3% (± 5.7%) after the completion of 16 weeks (P=0.000). Thirteen (45%) children recovered completely from malnutrition achieving a weight for length of >80; % whereas 15 (51.7%) recovered partly achieving weight for length >70;%. There was no death during the home stabilization. CONCLUSION: Home based management using home prepared food and hospital based follow up is associated with sub-optimal and slower recovery.
OBJECTIVE: To evaluate the feasibility and outcome of home-based rehabilitation of severely malnourished children. DESIGN: Prospective and observational. SETTING: Rehabilitation at home (16 weeks) following initial assessment or/and stabilization at hospital. PARTICIPANTS: Thirty-four severely malnourished (weight for length < 70% of WHO reference) children between the ages of 6 months to 5 years. INTERVENTION: Initial assessment of the patient was done in hospital. Those with complications or loss of appetite were admitted in hospital and managed as per WHO guidelines. After discharge, they were managed at home using home based diets. Those without complications and with preserved appetite were directly eligible for home-based rehabilitation. Follow up was done in hospital up to 16 weeks. Dietary intake, anthropometry and morbidities were recorded during follow-up. RESULTS: Of the enrolled 34 children, 19 children were admitted in hospital and 15 children were sent home after initial assessment in hospital. Five did not clear the initial stabilization phase (2 died, 3 left hospital). Finally 29 children qualified for home based rehabilitation out of which 26 completed 16 week follow-up. During the home based management phase, the reported mean (±SD) calorie intake increased from 100 (± 5) kcal/kg/d at entry point to 243 (± 13) kcal/kg/d at 16 weeks (P=0.000). Similarly, reported protein intake increased from 1.1 (± 0.3) g/kg/d to 4.8 (± 0.3) g/kg/d (P=0.000). During hospital stay (n=19), children had weight gain of 9.0 (±5.3) g/kg/d, while during home based follow up (n=29), weight gain was 3.2 (± 1.5) g/kg/d only. During home based rehabilitation, only 3 (11.5%) children had weight gain of more than 5 g/kg/d by the end of 16 weeks. Weight for height percent increased from an average (± SD) of 62.9% (± 6.0%) to 80.3% (± 5.7%) after the completion of 16 weeks (P=0.000). Thirteen (45%) children recovered completely from malnutrition achieving a weight for length of >80; % whereas 15 (51.7%) recovered partly achieving weight for length >70;%. There was no death during the home stabilization. CONCLUSION: Home based management using home prepared food and hospital based follow up is associated with sub-optimal and slower recovery.
Authors: Adino Tesfahun Tsegaye; Patricia B Pavlinac; Lynnth Turyagyenda; Abdoulaye H Diallo; Blaise S Gnoumou; Roseline M Bamouni; Wieger P Voskuijl; Meta van den Heuvel; Emmie Mbale; Christina L Lancioni; Ezekiel Mupere; John Mukisa; Christopher Lwanga; Michael Atuhairwe; Mohammod J Chisti; Tahmeed Ahmed; Abu S M S B Shahid; Ali F Saleem; Zaubina Kazi; Benson O Singa; Pholona Amam; Mary Masheti; James A Berkley; Judd L Walson; Kirkby D Tickell Journal: Nutrients Date: 2022-08-24 Impact factor: 6.706
Authors: Natasha Phillipa O'Sullivan; Natasha Lelijveld; Alexandra Rutishauser-Perera; Marko Kerac; Philip James Journal: PLoS One Date: 2018-08-30 Impact factor: 3.240