| Literature DB >> 20971825 |
Hamed Al-Hussaini1, Deepa Subramanyam, Michael Reedijk, Srikala S Sridhar.
Abstract
The highly conserved Notch signaling pathway is involved in regulating a number of key cellular processes. This pathway has been implicated in both the development and progression of breast cancer and has emerged as a possible therapeutic target. Several clinical trials are currently underway to determine if targeting the Notch pathway with drugs such as the γ-secretase inhibitors may be an effective therapeutic strategy that improves outcomes in this disease. ©2010 AACR.Entities:
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Year: 2010 PMID： 20971825 DOI： 10.1158/1535-7163.MCT-10-0677
Source DB: PubMed Journal: Mol Cancer Ther ISSN： 1535-7163 Impact factor: 6.261