Literature DB >> 20967579

Contemporary approaches to Alzheimer's disease and frontotemporal dementia.

Erik D Roberson1.   

Abstract

Alzheimer's disease and frontotemporal dementia are two of the most common neurodegenerative dementias. Here, we review the clinical presentation, genetic causes, typical neuropathology, and current treatments for these disorders. We then review molecules involved in their pathogenesis and protocols for working with these species and conclude with a discussion of experimental systems and outcome measures for studying these disorders.

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Year:  2011        PMID: 20967579     DOI: 10.1007/978-1-60761-744-0_1

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  5 in total

1.  A case report comparing clinical, imaging and neuropsychological assessment findings in twins discordant for the VCP p.R155C mutation.

Authors:  Abhilasha Surampalli; Brian T Gold; Charles Smith; Rudy J Castellani; Manaswitha Khare; Hon Yu; Celeste Nguyen; Mary Lan; Marie Wencel; Sharon Wigal; Vince Caiozzo; Virginia Kimonis
Journal:  Neuromuscul Disord       Date:  2014-10-22       Impact factor: 4.296

Review 2.  The multiple faces of valosin-containing protein-associated diseases: inclusion body myopathy with Paget's disease of bone, frontotemporal dementia, and amyotrophic lateral sclerosis.

Authors:  Angèle Nalbandian; Sandra Donkervoort; Eric Dec; Mallikarjun Badadani; Veeral Katheria; Prachi Rana; Christopher Nguyen; Jogeshwar Mukherjee; Vincent Caiozzo; Barbara Martin; Giles D Watts; Jouni Vesa; Charles Smith; Virginia E Kimonis
Journal:  J Mol Neurosci       Date:  2011-09-03       Impact factor: 3.444

Review 3.  Glial adenosine kinase--a neuropathological marker of the epileptic brain.

Authors:  Eleonora Aronica; Ursula S Sandau; Anand Iyer; Detlev Boison
Journal:  Neurochem Int       Date:  2013-02-04       Impact factor: 3.921

4.  Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia.

Authors:  Tara L Spires-Jones; Leora M Fox; Anete Rozkalne; Rose Pitstick; George A Carlson; Aleksey G Kazantsev
Journal:  Front Pharmacol       Date:  2012-03-12       Impact factor: 5.810

5.  Sex and gonadal hormones in mouse models of Alzheimer's disease: what is relevant to the human condition?

Authors:  Dena B Dubal; Lauren Broestl; Kurtresha Worden
Journal:  Biol Sex Differ       Date:  2012-11-05       Impact factor: 5.027

  5 in total

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