Literature DB >> 20966485

Type 2 diabetes in younger adults: the emerging UK epidemic.

Emma G Wilmot1, Melanie J Davies, Tom Yates, Katrien Benhalima, Ian G Lawrence, Kamlesh Khunti.   

Abstract

There is an emerging epidemic of type 2 diabetes (T2DM) in younger adults. They represent an extreme phenotype: likely to be obese, lead a sedentary lifestyle, have a strong family history of T2DM, be of black or minority ethnic origin, and come from less affluent socioeconomic groups. An accurate diagnosis of T2DM in younger adults, while essential to guide management, can be challenging even for the experienced diabetologist. Comorbidities such as hypertension, nephropathy and hyperlipidaemia are prevalent in this group, and, despite the lack of longitudinal data, they represent a very high risk group, with a need for aggressive management. This focused review of the epidemiology, aetiology, clinical outcomes, comorbidities and management of younger adults with T2DM will provide the non-specialist with up-to-date insight into the UK's emerging epidemic.

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Year:  2010        PMID: 20966485     DOI: 10.1136/pgmj.2010.100917

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  19 in total

Review 1.  Determining genetic risk factors for pediatric type 2 diabetes.

Authors:  Angharad R Morgan
Journal:  Curr Diab Rep       Date:  2012-02       Impact factor: 4.810

2.  Obesity and chronic disease in younger people: an unfolding crisis.

Authors:  Tom Yates; Melanie J Davies; Kamlesh Khunti
Journal:  Br J Gen Pract       Date:  2012-01       Impact factor: 5.386

Review 3.  The long-term metabolic and neurocognitive risks in offspring of women with type 1 diabetes mellitus.

Authors:  Gilles Vanhandsaeme; Katrien Benhalima
Journal:  Acta Diabetol       Date:  2021-03-15       Impact factor: 4.280

Review 4.  Is Diabetic Skeletal Fragility Associated with Microvascular Complications in Bone?

Authors:  Roberto Jose Fajardo
Journal:  Curr Osteoporos Rep       Date:  2017-02       Impact factor: 5.096

Review 5.  A review of rodent models of type 2 diabetic skeletal fragility.

Authors:  Roberto J Fajardo; Lamya Karim; Virginia I Calley; Mary L Bouxsein
Journal:  J Bone Miner Res       Date:  2014       Impact factor: 6.741

6.  Age and glycemic control among low-income Latinos.

Authors:  Diana M Naranjo; Elizabeth A Jacobs; Lawrence Fisher; Danielle Hessler; Alicia Fernandez
Journal:  J Immigr Minor Health       Date:  2013-10

Review 7.  Who should we target for diabetes prevention and diabetes risk reduction?

Authors:  Susann Blüher; Jana Markert; Sabine Herget; Thomas Yates; Melanie Davis; Gabriele Müller; Thomas Waldow; Peter E H Schwarz
Journal:  Curr Diab Rep       Date:  2012-04       Impact factor: 4.810

8.  Development and Validation of a Machine Learning Model Using Administrative Health Data to Predict Onset of Type 2 Diabetes.

Authors:  Mathieu Ravaut; Vinyas Harish; Hamed Sadeghi; Kin Kwan Leung; Maksims Volkovs; Kathy Kornas; Tristan Watson; Tomi Poutanen; Laura C Rosella
Journal:  JAMA Netw Open       Date:  2021-05-03

9.  A Randomised Controlled Trial to Reduce Sedentary Time in Young Adults at Risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time ANd Diabetes).

Authors:  Stuart J H Biddle; Charlotte L Edwardson; Emma G Wilmot; Thomas Yates; Trish Gorely; Danielle H Bodicoat; Nuzhat Ashra; Kamlesh Khunti; Myra A Nimmo; Melanie J Davies
Journal:  PLoS One       Date:  2015-12-01       Impact factor: 3.240

10.  Rationale and design of the randomised controlled trial to assess the impact of liraglutide on cardiac function and structure in young adults with type 2 diabetes (the LYDIA study).

Authors:  Z Z Htike; T Yates; E M Brady; D Webb; L J Gray; D Swarbrick; G P McCann; K Khunti; M J Davies
Journal:  Cardiovasc Diabetol       Date:  2016-07-21       Impact factor: 9.951

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