Literature DB >> 2096608

Treatment of intracranial meningiomas in patients over 70 years old.

C Arienta1, M Caroli, F Crotti, R Villani.   

Abstract

The neurosurgeon often finds himself in the position to having to decide whether or not to operate on an elderly patient suffering from intracranial meningioma. The decision is rarely easy and the results often disappointing. We studied 46 cases of intracranial meningioma in patients over 70 years of age, 34 patients were operated on while 12 patients were not, although both groups were subjected to long term follow-up. The operative mortality rate was 12%, a rate which increased to 20% at 3 months follow-up. Various unfavourable prognostic factors were taken into consideration, the most significant of which were: poor overall clinical condition, peritumoral oedema, the presence of diabetes mellitus and the duration of surgery. A scored grading system was created to standardize surgical indications in elderly patients with cerebral meningioma. An analysis of the grading system, when applied to patients submitted to surgery, showed that the decreased patients within 3 months of surgery had a score which varied from 7 to 12, with a mean score of 10. The surviving patients had a score averaging from 10 to 16 with a mean of 13. The patients with the lowest scores (7-9) had a 100% mortality rate while those in the upper ranges (13-16) demonstrated a mortality rate of 0%. Among the conservatively treated patients the worst outcome was seen in patients with a grading equal to or less than 12.

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Year:  1990        PMID: 2096608     DOI: 10.1007/bf01402612

Source DB:  PubMed          Journal:  Acta Neurochir (Wien)        ISSN: 0001-6268            Impact factor:   2.216


  11 in total

1.  The recurrence of intracranial meningiomas after surgical treatment.

Authors:  D SIMPSON
Journal:  J Neurol Neurosurg Psychiatry       Date:  1957-02       Impact factor: 10.154

2.  Intracranial meningiomas in the aged: surgical outcome in the era of computed tomography.

Authors:  I A Awad; I Kalfas; J F Hahn; J R Little
Journal:  Neurosurgery       Date:  1989-04       Impact factor: 4.654

3.  Intracranial meningiomas in the elderly (over 70 years old). A retrospective study of 30 surgical cases.

Authors:  M Djindjian; J P Caron; A A Athayde; M J Février
Journal:  Acta Neurochir (Wien)       Date:  1988       Impact factor: 2.216

4.  Biological features of meningiomas that determine the production of cerebral edema.

Authors:  H P Smith; V R Challa; D M Moody; D L Kelly
Journal:  Neurosurgery       Date:  1981-04       Impact factor: 4.654

Review 5.  Meningiomas: an update.

Authors:  D O Quest
Journal:  Neurosurgery       Date:  1978 Sep-Oct       Impact factor: 4.654

6.  Morbidity, mortality, and quality of life following surgery for intracranial meningiomas. A retrospective study in 257 cases.

Authors:  R C Chan; G B Thompson
Journal:  J Neurosurg       Date:  1984-01       Impact factor: 5.115

7.  Intracranial meningiomas in the elderly in the CT scan era.

Authors:  I Papo
Journal:  Acta Neurochir (Wien)       Date:  1983       Impact factor: 2.216

8.  Geriatric neurosurgery.

Authors:  M Dujovny; F Charbel; S K Berman; F G Diaz; G Malik; J I Ausman
Journal:  Surg Neurol       Date:  1987-07

9.  [Outcome of intracranial meningioma in adults. Retrospective study of a medicosurgical series of 161 meningiomas].

Authors:  M Jan; V Bazézé; D Saudeau; A Autret; P Bertrand; A Gouaze
Journal:  Neurochirurgie       Date:  1986       Impact factor: 1.553

10.  Meningioma: analysis of recurrence and progression following neurosurgical resection.

Authors:  R O Mirimanoff; D E Dosoretz; R M Linggood; R G Ojemann; R L Martuza
Journal:  J Neurosurg       Date:  1985-01       Impact factor: 5.115

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  11 in total

Review 1.  Pathogenesis of peri-tumoral edema in intracranial meningiomas.

Authors:  Moncef Berhouma; Timothee Jacquesson; Emmanuel Jouanneau; François Cotton
Journal:  Neurosurg Rev       Date:  2017-08-24       Impact factor: 3.042

2.  Definitive embolization of meningiomas. A review.

Authors:  B T Bateman; E Lin; J Pile-Spellman
Journal:  Interv Neuroradiol       Date:  2005-10-25       Impact factor: 1.610

3.  Trends in intracranial meningioma surgery and outcome: a Nationwide Inpatient Sample database analysis from 2001 to 2010.

Authors:  Sudheer Ambekar; Mayur Sharma; Venkatesh S Madhugiri; Anil Nanda
Journal:  J Neurooncol       Date:  2013-07-13       Impact factor: 4.130

4.  Interstitial radiotherapy of 25 parasellar/clival meningiomas and 19 meningiomas in the elderly. Analysis of short-term tolerance and responses.

Authors:  V Vuorinen; J Heikkonen; A Brander; K Setälä; T Sane; T Randell; A Paetau; J Pohjola; M Mäntylä; J Jääskeläinen
Journal:  Acta Neurochir (Wien)       Date:  1996       Impact factor: 2.216

5.  Brain oedema in patients with intracranial meningioma. Correlation between clinical, radiological, and histological factors and the presence and intensity of oedema.

Authors:  R D Lobato; R Alday; P A Gómez; J J Rivas; J Domínguez; A Cabrera; S Madero; J Ayerbe
Journal:  Acta Neurochir (Wien)       Date:  1996       Impact factor: 2.216

6.  Prognostic implications of meningiomas in the elderly (over 70 years old) in the era of magnetic resonance imaging.

Authors:  T Nishizaki; T Kamiryo; H Fujisawa; N Ohshita; H Ishihara; H Ito; H Aoki
Journal:  Acta Neurochir (Wien)       Date:  1994       Impact factor: 2.216

7.  Role of pia mater vascularization of the tumour in the surgical outcome of intracranial meningiomas.

Authors:  M Sindou; M Alaywan
Journal:  Acta Neurochir (Wien)       Date:  1994       Impact factor: 2.216

8.  Outcome comparison between younger and older patients undergoing intracranial meningioma resections.

Authors:  Michael Tin-Chung Poon; Linus Hing-Kai Fung; Jenny Kan-Suen Pu; Gilberto Ka-Kit Leung
Journal:  J Neurooncol       Date:  2013-06-05       Impact factor: 4.130

9.  Rapid and Accurate MRI Segmentation of Peritumoral Brain Edema in Meningiomas.

Authors:  F Latini; E-M Larsson; M Ryttlefors
Journal:  Clin Neuroradiol       Date:  2015-11-24       Impact factor: 3.649

10.  Meningioma Surgery in Patients ≥70 Years of Age: Clinical Outcome and Validation of the SKALE Score.

Authors:  Daniel Monden; Florian J Raimann; Vanessa Neef; Daniel Dubinski; Florian Gessler; Fee Keil; Marie-Thérèse Forster; Michael W Ronellenfitsch; Patrick N Harter; Thomas M Freiman; Elke Hattingen; Volker Seifert; Christian Senft; Peter Baumgarten
Journal:  J Clin Med       Date:  2021-04-22       Impact factor: 4.241

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